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PHOX2B-mediated regulation of ALK expression: in vitro identification of a functional relationship between two genes involved in neuroblastoma.
Bachetti T, Di Paolo D, Di Lascio S, Mirisola V, Brignole C, Bellotti M, Caffa I, Ferraris C, Fiore M, Fornasari D, Chiarle R, Borghini S, Pfeffer U, Ponzoni M, Ceccherini I, Perri P. Bachetti T, et al. Among authors: di lascio s, di paolo d. PLoS One. 2010 Oct 1;5(10):e13108. doi: 10.1371/journal.pone.0013108. PLoS One. 2010. PMID: 20957039 Free PMC article.
Neuroblastoma-targeted nanoparticles entrapping siRNA specifically knockdown ALK.
Di Paolo D, Brignole C, Pastorino F, Carosio R, Zorzoli A, Rossi M, Loi M, Pagnan G, Emionite L, Cilli M, Bruno S, Chiarle R, Allen TM, Ponzoni M, Perri P. Di Paolo D, et al. Mol Ther. 2011 Jun;19(6):1131-40. doi: 10.1038/mt.2011.54. Epub 2011 Apr 12. Mol Ther. 2011. PMID: 21487394 Free PMC article.
Ligand-targeted liposomal therapies of neuroblastoma.
Pastorino F, Marimpietri D, Brignole C, Di Paolo D, Pagnan G, Daga A, Piccardi F, Cilli M, Allen TM, Ponzoni M. Pastorino F, et al. Among authors: di paolo d. Curr Med Chem. 2007;14(29):3070-8. doi: 10.2174/092986707782793916. Curr Med Chem. 2007. PMID: 18220743 Review.
Liposome-mediated therapy of neuroblastoma.
Di Paolo D, Loi M, Pastorino F, Brignole C, Marimpietri D, Becherini P, Caffa I, Zorzoli A, Longhi R, Gagliani C, Tacchetti C, Corti A, Allen TM, Ponzoni M, Pagnan G. Di Paolo D, et al. Methods Enzymol. 2009;465:225-49. doi: 10.1016/S0076-6879(09)65012-6. Methods Enzymol. 2009. PMID: 19913170
Therapeutic targeting of TLR9 inhibits cell growth and induces apoptosis in neuroblastoma.
Brignole C, Marimpietri D, Di Paolo D, Perri P, Morandi F, Pastorino F, Zorzoli A, Pagnan G, Loi M, Caffa I, Erminio G, Haupt R, Gambini C, Pistoia V, Ponzoni M. Brignole C, et al. Among authors: di paolo d. Cancer Res. 2010 Dec 1;70(23):9816-26. doi: 10.1158/0008-5472.CAN-10-1251. Epub 2010 Oct 8. Cancer Res. 2010. PMID: 20935225
Selective therapeutic targeting of the anaplastic lymphoma kinase with liposomal siRNA induces apoptosis and inhibits angiogenesis in neuroblastoma.
Di Paolo D, Ambrogio C, Pastorino F, Brignole C, Martinengo C, Carosio R, Loi M, Pagnan G, Emionite L, Cilli M, Ribatti D, Allen TM, Chiarle R, Ponzoni M, Perri P. Di Paolo D, et al. Mol Ther. 2011 Dec;19(12):2201-12. doi: 10.1038/mt.2011.142. Epub 2011 Aug 9. Mol Ther. 2011. PMID: 21829174 Free PMC article.
New therapeutic strategies in neuroblastoma: combined targeting of a novel tyrosine kinase inhibitor and liposomal siRNAs against ALK.
Di Paolo D, Yang D, Pastorino F, Emionite L, Cilli M, Daga A, Destafanis E, Di Fiore A, Piaggio F, Brignole C, Xu X, Liang C, Gibbons J, Ponzoni M, Perri P. Di Paolo D, et al. Among authors: di fiore a. Oncotarget. 2015 Oct 6;6(30):28774-89. doi: 10.18632/oncotarget.4342. Oncotarget. 2015. PMID: 26299615 Free PMC article.
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