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Isoprostanes inhibit vascular endothelial growth factor-induced endothelial cell migration, tube formation, and cardiac vessel sprouting in vitro, as well as angiogenesis in vivo via activation of the thromboxane A(2) receptor: a potential link between oxidative stress and impaired angiogenesis.
Benndorf RA, Schwedhelm E, Gnann A, Taheri R, Kom G, Didié M, Steenpass A, Ergün S, Böger RH. Benndorf RA, et al. Circ Res. 2008 Oct 24;103(9):1037-46. doi: 10.1161/CIRCRESAHA.108.184036. Epub 2008 Sep 18. Circ Res. 2008. PMID: 18802021
A prognostic model predicted deterioration in health-related quality of life in older patients with multimorbidity and polypharmacy.
González-González AI, Meid AD, Dinh TS, Blom JW, van den Akker M, Elders PJM, Thiem U, De Gaudry DK, Swart KMA, Rudolf H, Bosch-Lenders D, Trampisch HJ, Meerpohl JJ, Gerlach FM, Flaig B, Kom G, Snell KIE, Perera R, Haefeli WE, Glasziou PP, Muth C. González-González AI, et al. J Clin Epidemiol. 2021 Feb;130:1-12. doi: 10.1016/j.jclinepi.2020.10.006. Epub 2020 Oct 13. J Clin Epidemiol. 2021. PMID: 33065164
Predicting negative health outcomes in older general practice patients with chronic illness: Rationale and development of the PROPERmed harmonized individual participant data database.
González-González AI, Dinh TS, Meid AD, Blom JW, van den Akker M, Elders PJM, Thiem U, Kuellenberg de Gaudry D, Snell KIE, Perera R, Swart KMA, Rudolf H, Bosch-Lenders D, Trampisch HJ, Meerpohl JJ, Flaig B, Kom G, Gerlach FM, Hafaeli WE, Glasziou PP, Muth C. González-González AI, et al. Mech Ageing Dev. 2021 Mar;194:111436. doi: 10.1016/j.mad.2021.111436. Epub 2021 Jan 15. Mech Ageing Dev. 2021. PMID: 33460622
Predicting hospital admissions from individual patient data (IPD): an applied example to explore key elements driving external validity.
Meid AD, Gonzalez-Gonzalez AI, Dinh TS, Blom J, van den Akker M, Elders P, Thiem U, Küllenberg de Gaudry D, Swart KMA, Rudolf H, Bosch-Lenders D, Trampisch HJ, Meerpohl JJ, Gerlach FM, Flaig B, Kom G, Snell KIE, Perera R, Haefeli WE, Glasziou P, Muth C. Meid AD, et al. BMJ Open. 2021 Aug 4;11(8):e045572. doi: 10.1136/bmjopen-2020-045572. BMJ Open. 2021. PMID: 34348947 Free PMC article.