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A phase 2b double-blind placebo-controlled randomized clinical trial of SB-061, an aggrecan mimetic, in patients with symptomatic knee osteoarthritis.
Bihlet AR, Byrjalsen I, Mundbjerg K, Rovsing H, Axelsen TM, Andersen JR, Metnik A, Bachtell N, Brett A, Alexandersen P. Bihlet AR, et al. Among authors: bachtell n. Osteoarthritis Cartilage. 2024 Nov;32(11):1471-1480. doi: 10.1016/j.joca.2024.06.016. Epub 2024 Jul 1. Osteoarthritis Cartilage. 2024. PMID: 38960141 Clinical Trial.
Localized inhibition of platelets and platelet derived growth factor by a matrix targeted glycan mimetic significantly attenuates liver fibrosis.
Kabra H, Walimbe T, Stuart K, Indey C, Jalgaonkar S, Ikwa E, Skurnac T, Chen J, Woolley A, Snead NM, Bachtell N, Leeming DJ, Karsdal M, Prestwich G, Panitch A, Paderi J. Kabra H, et al. Among authors: bachtell n. Biomaterials. 2021 Feb;269:120538. doi: 10.1016/j.biomaterials.2020.120538. Epub 2020 Nov 17. Biomaterials. 2021. PMID: 33246740
Methodologic issues in clinical trials for prevention or risk reduction in osteoarthritis.
Jordan JM, Sowers MF, Messier SP, Bradley J, Arangio G, Katz JN, Losina E, Rovati L, Bachtell N, Cooper C, Spector T, Zhang W, Gardiner J, Wahba M. Jordan JM, et al. Among authors: bachtell n. Osteoarthritis Cartilage. 2011 May;19(5):500-8. doi: 10.1016/j.joca.2010.10.031. Epub 2011 Mar 23. Osteoarthritis Cartilage. 2011. PMID: 21396470 Free PMC article.