McDonnell DP - Search Results

1

Mechanisms of progesterone receptor inhibition of inflammatory responses in cellular models of breast cancer.

Kobayashi S, Stice JP, Kazmin D, Wittmann BM, Kimbrel EA, Edwards DP, Chang CY, McDonnell DP. Kobayashi S, et al. Among authors: mcdonnell dp. Mol Endocrinol. 2010 Dec;24(12):2292-302. doi: 10.1210/me.2010-0289. Epub 2010 Oct 27. Mol Endocrinol. 2010. PMID: 20980435 Free PMC article.

2

Cellular mechanisms which distinguish between hormone- and antihormone-activated estrogen receptor.

McDonnell DP, Dana SL, Hoener PA, Lieberman BA, Imhof MO, Stein RB. McDonnell DP, et al. Ann N Y Acad Sci. 1995 Jun 12;761:121-37. doi: 10.1111/j.1749-6632.1995.tb31374.x. Ann N Y Acad Sci. 1995. PMID: 7625716 Review.

3

Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions.

Tzukerman MT, Esty A, Santiso-Mere D, Danielian P, Parker MG, Stein RB, Pike JW, McDonnell DP. Tzukerman MT, et al. Among authors: mcdonnell dp. Mol Endocrinol. 1994 Jan;8(1):21-30. doi: 10.1210/mend.8.1.8152428. Mol Endocrinol. 1994. PMID: 8152428

4

Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function.

Vegeto E, Shahbaz MM, Wen DX, Goldman ME, O'Malley BW, McDonnell DP. Vegeto E, et al. Among authors: mcdonnell dp. Mol Endocrinol. 1993 Oct;7(10):1244-55. doi: 10.1210/mend.7.10.8264658. Mol Endocrinol. 1993. PMID: 8264658

5

Analysis of estrogen receptor function in vitro reveals three distinct classes of antiestrogens.

McDonnell DP, Clemm DL, Hermann T, Goldman ME, Pike JW. McDonnell DP, et al. Mol Endocrinol. 1995 Jun;9(6):659-69. doi: 10.1210/mend.9.6.8592512. Mol Endocrinol. 1995. PMID: 8592512

6

16 alpha-substituted analogs of the antiprogestin RU486 induce a unique conformation in the human progesterone receptor resulting in mixed agonist activity.

Wagner BL, Pollio G, Leonhardt S, Wani MC, Lee DY, Imhof MO, Edwards DP, Cook CE, McDonnell DP. Wagner BL, et al. Among authors: mcdonnell dp. Proc Natl Acad Sci U S A. 1996 Aug 6;93(16):8739-44. doi: 10.1073/pnas.93.16.8739. Proc Natl Acad Sci U S A. 1996. PMID: 8710941 Free PMC article.

7

Identification of the sequences within the human complement 3 promoter required for estrogen responsiveness provides insight into the mechanism of tamoxifen mixed agonist activity.

Fan JD, Wagner BL, McDonnell DP. Fan JD, et al. Among authors: mcdonnell dp. Mol Endocrinol. 1996 Dec;10(12):1605-16. doi: 10.1210/mend.10.12.8961270. Mol Endocrinol. 1996. PMID: 8961270

8

Identification of a third autonomous activation domain within the human estrogen receptor.

Norris JD, Fan D, Kerner SA, McDonnell DP. Norris JD, et al. Among authors: mcdonnell dp. Mol Endocrinol. 1997 Jun;11(6):747-54. doi: 10.1210/mend.11.6.0008. Mol Endocrinol. 1997. PMID: 9171238

9

Mapping and characterization of the functional domains responsible for the differential activity of the A and B isoforms of the human progesterone receptor.

Giangrande PH, Pollio G, McDonnell DP. Giangrande PH, et al. Among authors: mcdonnell dp. J Biol Chem. 1997 Dec 26;272(52):32889-900. doi: 10.1074/jbc.272.52.32889. J Biol Chem. 1997. PMID: 9407067 Free article.

10

The nuclear corepressors NCoR and SMRT are key regulators of both ligand- and 8-bromo-cyclic AMP-dependent transcriptional activity of the human progesterone receptor.

Wagner BL, Norris JD, Knotts TA, Weigel NL, McDonnell DP. Wagner BL, et al. Among authors: mcdonnell dp. Mol Cell Biol. 1998 Mar;18(3):1369-78. doi: 10.1128/MCB.18.3.1369. Mol Cell Biol. 1998. PMID: 9488452 Free PMC article.

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