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An open-label, single-arm Phase II study of intravenous weekly (Days 1 and 8) topotecan in combination with carboplatin (Day 1) every 21 days as second-line therapy in patients with platinum-sensitive relapsed ovarian cancer.
Rose PG, Monk BJ, Provencher D, Hartney J, Legenne P, Lane S. Rose PG, et al. Among authors: hartney j. Gynecol Oncol. 2011 Jan;120(1):38-42. doi: 10.1016/j.ygyno.2010.10.011. Epub 2010 Nov 5. Gynecol Oncol. 2011. PMID: 21055798 Clinical Trial.
A phase I study to characterize the safety, tolerability, and pharmacokinetics of topotecan at 4 mg/m2 administered weekly as a 30-minute intravenous infusion in patients with cancer.
Curtis KK, Hartney JT, Jewell RC, Park JW, Lebowitz PF, Griffin PP, Borad MJ, Fitch TR, Northfelt DW. Curtis KK, et al. Among authors: hartney jt. J Clin Pharmacol. 2010 Mar;50(3):268-75. doi: 10.1177/0091270009343699. Epub 2009 Oct 6. J Clin Pharmacol. 2010. PMID: 19808951 Clinical Trial.
Long-Term Outcomes in Patients With Connective Tissue Disease-Associated Pulmonary Arterial Hypertension in the Modern Treatment Era: Meta-Analyses of Randomized, Controlled Trials and Observational Registries.
Khanna D, Zhao C, Saggar R, Mathai SC, Chung L, Coghlan JG, Shah M, Hartney J, McLaughlin V. Khanna D, et al. Among authors: hartney j. Arthritis Rheumatol. 2021 May;73(5):837-847. doi: 10.1002/art.41669. Epub 2021 Mar 29. Arthritis Rheumatol. 2021. PMID: 33538058 Free PMC article.
Human IL-32 expression protects mice against a hypervirulent strain of Mycobacterium tuberculosis.
Bai X, Shang S, Henao-Tamayo M, Basaraba RJ, Ovrutsky AR, Matsuda JL, Takeda K, Chan MM, Dakhama A, Kinney WH, Trostel J, Bai A, Honda JR, Achcar R, Hartney J, Joosten LA, Kim SH, Orme I, Dinarello CA, Ordway DJ, Chan ED. Bai X, et al. Among authors: hartney j. Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):5111-6. doi: 10.1073/pnas.1424302112. Epub 2015 Mar 27. Proc Natl Acad Sci U S A. 2015. PMID: 25820174 Free PMC article.
A common polymorphism in extracellular superoxide dismutase affects cardiopulmonary disease risk by altering protein distribution.
Hartney JM, Stidham T, Goldstrohm DA, Oberley-Deegan RE, Weaver MR, Valnickova-Hansen Z, Scavenius C, Benninger RK, Leahy KF, Johnson R, Gally F, Kosmider B, Zimmermann AK, Enghild JJ, Nozik-Grayck E, Bowler RP. Hartney JM, et al. Circ Cardiovasc Genet. 2014 Oct;7(5):659-66. doi: 10.1161/CIRCGENETICS.113.000504. Epub 2014 Aug 1. Circ Cardiovasc Genet. 2014. PMID: 25085920 Free PMC article.
The cellular distribution of extracellular superoxide dismutase in macrophages is altered by cellular activation but unaffected by the naturally occurring R213G substitution.
Gottfredsen RH, Goldstrohm DA, Hartney JM, Larsen UG, Bowler RP, Petersen SV. Gottfredsen RH, et al. Among authors: hartney jm. Free Radic Biol Med. 2014 Apr;69:348-56. doi: 10.1016/j.freeradbiomed.2014.01.038. Epub 2014 Feb 7. Free Radic Biol Med. 2014. PMID: 24512907 Free PMC article.
30 results