Kool J - Search Results

1

Recent developments in protein-ligand affinity mass spectrometry.

Jonker N, Kool J, Irth H, Niessen WM. Jonker N, et al. Among authors: kool j. Anal Bioanal Chem. 2011 Mar;399(8):2669-81. doi: 10.1007/s00216-010-4350-z. Epub 2010 Nov 8. Anal Bioanal Chem. 2011. PMID: 21058031 Free PMC article. Review.

2

Development and validation of a microsomal online cytochrome P450 bioreactor coupled to solid-phase extraction and reversed-phase liquid chromatography.

van Liempd SM, Kool J, Reinen J, Schenk T, Meerman JH, Irth H, Vermeulen NP. van Liempd SM, et al. Among authors: kool j. J Chromatogr A. 2005 May 20;1075(1-2):205-12. doi: 10.1016/j.chroma.2005.03.084. J Chromatogr A. 2005. PMID: 15974134

3

Development of a novel cytochrome p450 bioaffinity detection system coupled online to gradient reversed-phase high-performance liquid chromatography.

Kool J, van Liempd SM, Ramautar R, Schenk T, Meerman JH, Irth H, Commandeur JN, Vermeulen NP. Kool J, et al. J Biomol Screen. 2005 Aug;10(5):427-36. doi: 10.1177/1087057105274904. J Biomol Screen. 2005. PMID: 16093552

4

Rapid on-line profiling of estrogen receptor binding metabolites of tamoxifen.

Kool J, Ramautar R, van Liempd SM, Beckman J, de Kanter FJ, Meerman JH, Schenk T, Irth H, Commandeur JN, Vermeulen NP. Kool J, et al. J Med Chem. 2006 Jun 1;49(11):3287-92. doi: 10.1021/jm0507936. J Med Chem. 2006. PMID: 16722647

5

On-line formation, separation, and estrogen receptor affinity screening of cytochrome P450-derived metabolites of selective estrogen receptor modulators.

van Liempd SM, Kool J, Niessen WM, van Elswijk DE, Irth H, Vermeulen NP. van Liempd SM, et al. Among authors: kool j. Drug Metab Dispos. 2006 Sep;34(9):1640-9. doi: 10.1124/dmd.106.010355. Epub 2006 Jun 21. Drug Metab Dispos. 2006. PMID: 16790557

6

Development of three parallel cytochrome P450 enzyme affinity detection systems coupled on-line to gradient high-performance liquid chromatography.

Kool J, van Liempd SM, van Rossum H, van Elswijk DA, Irth H, Commandeur JN, Vermeulen NP. Kool J, et al. Drug Metab Dispos. 2007 Apr;35(4):640-8. doi: 10.1124/dmd.106.012245. Epub 2007 Jan 24. Drug Metab Dispos. 2007. PMID: 17251308

7

Online biochemical detection of glutathione-S-transferase P1-specific inhibitors in complex mixtures.

Kool J, Eggink M, van Rossum H, van Liempd SM, van Elswijk DA, Irth H, Commandeur JN, Meerman JH, Vermeulen NP. Kool J, et al. J Biomol Screen. 2007 Apr;12(3):396-405. doi: 10.1177/1087057107299527. Epub 2007 Mar 22. J Biomol Screen. 2007. PMID: 17379858

8

An on-line post-column detection system for the detection of reactive-oxygen-species-producing compounds and antioxidants in mixtures.

Kool J, Van Liempd SM, Harmsen S, Schenk T, Irth H, Commandeur JN, Vermeulen NP. Kool J, et al. Anal Bioanal Chem. 2007 Jun;388(4):871-9. doi: 10.1007/s00216-007-1296-x. Epub 2007 Apr 28. Anal Bioanal Chem. 2007. PMID: 17468853 Free PMC article.

9

Cytochrome P450 bio-affinity detection coupled to gradient HPLC: on-line screening of affinities to cytochrome P4501A2 and 2D6.

Kool J, van Liempd SM, Harmsen S, Beckman J, van Elswijk D, Commandeur JN, Irth H, Vermeulen NP. Kool J, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Oct 15;858(1-2):49-58. doi: 10.1016/j.jchromb.2007.08.005. Epub 2007 Aug 17. J Chromatogr B Analyt Technol Biomed Life Sci. 2007. PMID: 17826363

10

Metabolic profiling of endocrine-disrupting compounds by on-line cytochrome p450 bioreaction coupled to on-line receptor affinity screening.

Van Liempd SM, Kool J, Meerman JH, Irth H, Vermeulen NP. Van Liempd SM, et al. Among authors: kool j. Chem Res Toxicol. 2007 Dec;20(12):1825-32. doi: 10.1021/tx7000724. Epub 2007 Nov 1. Chem Res Toxicol. 2007. PMID: 17975887

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