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Xanthine oxidoreductase promotes the inflammatory state of mononuclear phagocytes through effects on chemokine expression, peroxisome proliferator-activated receptor-{gamma} sumoylation, and HIF-1{alpha}.
Gibbings S, Elkins ND, Fitzgerald H, Tiao J, Weyman ME, Shibao G, Fini MA, Wright RM. Gibbings S, et al. Among authors: weyman me. J Biol Chem. 2011 Jan 14;286(2):961-75. doi: 10.1074/jbc.M110.150847. Epub 2010 Nov 8. J Biol Chem. 2011. PMID: 21059659 Free PMC article.