Lou B - Search Results

1

Synthesis and identification of new 4-arylidene curcumin analogues as potential anticancer agents targeting nuclear factor-κB signaling pathway.

Qiu X, Du Y, Lou B, Zuo Y, Shao W, Huo Y, Huang J, Yu Y, Zhou B, Du J, Fu H, Bu X. Qiu X, et al. Among authors: lou b. J Med Chem. 2010 Dec 9;53(23):8260-73. doi: 10.1021/jm1004545. Epub 2010 Nov 11. J Med Chem. 2010. PMID: 21070043 Free PMC article.

2

Activation of the p38 pathway by a novel monoketone curcumin analog, EF24, suggests a potential combination strategy.

Thomas SL, Zhao J, Li Z, Lou B, Du Y, Purcell J, Snyder JP, Khuri FR, Liotta D, Fu H. Thomas SL, et al. Among authors: lou b. Biochem Pharmacol. 2010 Nov 1;80(9):1309-16. doi: 10.1016/j.bcp.2010.06.048. Epub 2010 Jul 6. Biochem Pharmacol. 2010. PMID: 20615389 Free PMC article.

3

A time-resolved fluorescence resonance energy transfer assay for high-throughput screening of 14-3-3 protein-protein interaction inhibitors.

Du Y, Fu RW, Lou B, Zhao J, Qui M, Khuri FR, Fu H. Du Y, et al. Among authors: lou b. Assay Drug Dev Technol. 2013 Jul;11(6):367-81. doi: 10.1089/adt.2013.507. Epub 2013 Aug 1. Assay Drug Dev Technol. 2013. PMID: 23906346 Free PMC article.

4

Identification of small molecule sphingomyelin synthase inhibitors.

Deng X, Lin F, Zhang Y, Li Y, Zhou L, Lou B, Li Y, Dong J, Ding T, Jiang X, Wang R, Ye D. Deng X, et al. Among authors: lou b. Eur J Med Chem. 2014 Feb 12;73:1-7. doi: 10.1016/j.ejmech.2013.12.002. Epub 2013 Dec 14. Eur J Med Chem. 2014. PMID: 24374347

5

Discovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitor.

Zhao J, Du Y, Horton JR, Upadhyay AK, Lou B, Bai Y, Zhang X, Du L, Li M, Wang B, Zhang L, Barbieri JT, Khuri FR, Cheng X, Fu H. Zhao J, et al. Among authors: lou b. Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16212-6. doi: 10.1073/pnas.1100012108. Epub 2011 Sep 9. Proc Natl Acad Sci U S A. 2011. PMID: 21908710 Free PMC article.

6

Discovery, synthesis and anti-atherosclerotic activities of a novel selective sphingomyelin synthase 2 inhibitor.

Li Y, Huang T, Lou B, Ye D, Qi X, Li X, Hu S, Ding T, Chen Y, Cao Y, Mo M, Dong J, Wei M, Chu Y, Li H, Jiang XC, Cheng N, Zhou L. Li Y, et al. Among authors: lou b. Eur J Med Chem. 2019 Feb 1;163:864-882. doi: 10.1016/j.ejmech.2018.12.028. Epub 2018 Dec 13. Eur J Med Chem. 2019. PMID: 30580239

7

Pharmacologic inhibition of sphingomyelin synthase (SMS) activity reduces apolipoprotein-B secretion from hepatocytes and attenuates endotoxin-mediated macrophage inflammation.

Lou B, Dong J, Li Y, Ding T, Bi T, Li Y, Deng X, Ye D, Jiang XC. Lou B, et al. PLoS One. 2014 Jul 17;9(7):e102641. doi: 10.1371/journal.pone.0102641. eCollection 2014. PLoS One. 2014. PMID: 25032960 Free PMC article.

8

2-Hydroxy-oleic acid does not activate sphingomyelin synthase activity.

Lou B, Liu Q, Hou J, Kabir I, Liu P, Ding T, Dong J, Mo M, Ye D, Chen Y, Bui HH, Roth K, Cao Y, Jiang XC. Lou B, et al. J Biol Chem. 2018 Nov 23;293(47):18328-18336. doi: 10.1074/jbc.RA118.005904. Epub 2018 Oct 10. J Biol Chem. 2018. PMID: 30305392 Free PMC article.

9

Adenovirus-mediated overexpression of sphingomyelin synthases 1 and 2 increases the atherogenic potential in mice.

Dong J, Liu J, Lou B, Li Z, Ye X, Wu M, Jiang XC. Dong J, et al. Among authors: lou b. J Lipid Res. 2006 Jun;47(6):1307-14. doi: 10.1194/jlr.M600040-JLR200. Epub 2006 Feb 28. J Lipid Res. 2006. PMID: 16508036 Free article.

10

Sphingomyelin synthase 2 facilitates M2-like macrophage polarization and tumor progression in a mouse model of triple-negative breast cancer.

Deng Y, Hu JC, He SH, Lou B, Ding TB, Yang JT, Mo MG, Ye DY, Zhou L, Jiang XC, Yu K, Dong JB. Deng Y, et al. Among authors: lou b. Acta Pharmacol Sin. 2021 Jan;42(1):149-159. doi: 10.1038/s41401-020-0419-1. Epub 2020 May 25. Acta Pharmacol Sin. 2021. PMID: 32451413 Free PMC article.

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