Levites Y - Search Results

1

Inhibiting β-secretase activity in Alzheimer's disease cell models with single-chain antibodies specifically targeting APP.

Boddapati S, Levites Y, Sierks MR. Boddapati S, et al. Among authors: levites y. J Mol Biol. 2011 Jan 14;405(2):436-47. doi: 10.1016/j.jmb.2010.10.054. Epub 2010 Nov 10. J Mol Biol. 2011. PMID: 21073877

2

Proteomic changes in the human cerebrovasculature in Alzheimer's disease and related tauopathies linked to peripheral biomarkers in plasma and cerebrospinal fluid.

Wojtas AM, Dammer EB, Guo Q, Ping L, Shantaraman A, Duong DM, Yin L, Fox EJ, Seifar F, Lee EB, Johnson ECB, Lah JJ, Levey AI, Levites Y, Rangaraju S, Golde TE, Seyfried NT. Wojtas AM, et al. Among authors: levites y. Alzheimers Dement. 2024 Jun;20(6):4043-4065. doi: 10.1002/alz.13821. Epub 2024 May 7. Alzheimers Dement. 2024. PMID: 38713744 Free PMC article.

3

Proteomic Changes in the Human Cerebrovasculature in Alzheimer's Disease and Related Tauopathies Linked to Peripheral Biomarkers in Plasma and Cerebrospinal Fluid.

Wojtas AM, Dammer EB, Guo Q, Ping L, Shantaraman A, Duong DM, Yin L, Fox EJ, Seifar F, Lee EB, Johnson ECB, Lah JJ, Levey AI, Levites Y, Rangaraju S, Golde TE, Seyfried NT. Wojtas AM, et al. Among authors: levites y. medRxiv [Preprint]. 2024 Jan 11:2024.01.10.24301099. doi: 10.1101/2024.01.10.24301099. medRxiv. 2024. Update in: Alzheimers Dement. 2024 Jun;20(6):4043-4065. doi: 10.1002/alz.13821 PMID: 38260316 Free PMC article. Updated. Preprint.

4

Insights into the mechanisms of action of anti-Abeta antibodies in Alzheimer's disease mouse models.

Levites Y, Smithson LA, Price RW, Dakin RS, Yuan B, Sierks MR, Kim J, McGowan E, Reed DK, Rosenberry TL, Das P, Golde TE. Levites Y, et al. FASEB J. 2006 Dec;20(14):2576-8. doi: 10.1096/fj.06-6463fje. Epub 2006 Oct 26. FASEB J. 2006. PMID: 17068112

5

Bispecific tandem single chain antibody simultaneously inhibits β-secretase and promotes α-secretase processing of AβPP.

Boddapati S, Levites Y, Suryadi V, Kasturirangan S, Sierks MR. Boddapati S, et al. Among authors: levites y. J Alzheimers Dis. 2012;28(4):961-9. doi: 10.3233/JAD-2011-111196. J Alzheimers Dis. 2012. PMID: 22156046

6

Anti-Aβ single-chain variable fragment antibodies exert synergistic neuroprotective activities in Drosophila models of Alzheimer's disease.

Fernandez-Funez P, Zhang Y, Sanchez-Garcia J, de Mena L, Khare S, Golde TE, Levites Y, Rincon-Limas DE. Fernandez-Funez P, et al. Among authors: levites y. Hum Mol Genet. 2015 Nov 1;24(21):6093-105. doi: 10.1093/hmg/ddv321. Epub 2015 Aug 7. Hum Mol Genet. 2015. PMID: 26253732 Free PMC article.

7

Soluble α-synuclein-antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia.

Trudler D, Nazor KL, Eisele YS, Grabauskas T, Dolatabadi N, Parker J, Sultan A, Zhong Z, Goodwin MS, Levites Y, Golde TE, Kelly JW, Sierks MR, Schork NJ, Karin M, Ambasudhan R, Lipton SA. Trudler D, et al. Among authors: levites y. Proc Natl Acad Sci U S A. 2021 Apr 13;118(15):e2025847118. doi: 10.1073/pnas.2025847118. Proc Natl Acad Sci U S A. 2021. PMID: 33833060 Free PMC article.

8

Generating differentially targeted amyloid-beta specific intrabodies as a passive vaccination strategy for Alzheimer's disease.

Sudol KL, Mastrangelo MA, Narrow WC, Frazer ME, Levites YR, Golde TE, Federoff HJ, Bowers WJ. Sudol KL, et al. Mol Ther. 2009 Dec;17(12):2031-40. doi: 10.1038/mt.2009.174. Epub 2009 Jul 28. Mol Ther. 2009. PMID: 19638957 Free PMC article.

9

Intracerebral but Not Peripheral Infection of Live Porphyromonas gingivalis Exacerbates Alzheimer's Disease Like Amyloid Pathology in APP-TgCRND8 Mice.

Aravindraja C, Sakthivel R, Liu X, Goodwin M, Veena P, Godovikova V, Fenno JC, Levites Y, Golde TE, Kesavalu L. Aravindraja C, et al. Among authors: levites y. Int J Mol Sci. 2022 Mar 19;23(6):3328. doi: 10.3390/ijms23063328. Int J Mol Sci. 2022. PMID: 35328748 Free PMC article.

10

AAV-mediated delivery of an anti-BACE1 VHH alleviates pathology in an Alzheimer's disease model.

Marino M, Zhou L, Rincon MY, Callaerts-Vegh Z, Verhaert J, Wahis J, Creemers E, Yshii L, Wierda K, Saito T, Marneffe C, Voytyuk I, Wouters Y, Dewilde M, Duqué SI, Vincke C, Levites Y, Golde TE, Saido TC, Muyldermans S, Liston A, De Strooper B, Holt MG. Marino M, et al. Among authors: levites y. EMBO Mol Med. 2022 Apr 7;14(4):e09824. doi: 10.15252/emmm.201809824. Epub 2022 Mar 30. EMBO Mol Med. 2022. PMID: 35352880 Free PMC article.

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