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CD14 is a coreceptor of Toll-like receptors 7 and 9.
Baumann CL, Aspalter IM, Sharif O, Pichlmair A, Blüml S, Grebien F, Bruckner M, Pasierbek P, Aumayr K, Planyavsky M, Bennett KL, Colinge J, Knapp S, Superti-Furga G. Baumann CL, et al. Among authors: pichlmair a. J Exp Med. 2010 Nov 22;207(12):2689-701. doi: 10.1084/jem.20101111. Epub 2010 Nov 15. J Exp Med. 2010. PMID: 21078886 Free PMC article.
SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.
Schmidt N, Ganskih S, Wei Y, Gabel A, Zielinski S, Keshishian H, Lareau CA, Zimmermann L, Makroczyova J, Pearce C, Krey K, Hennig T, Stegmaier S, Moyon L, Horlacher M, Werner S, Aydin J, Olguin-Nava M, Potabattula R, Kibe A, Dölken L, Smyth RP, Caliskan N, Marsico A, Krempl C, Bodem J, Pichlmair A, Carr SA, Chlanda P, Erhard F, Munschauer M. Schmidt N, et al. Among authors: pichlmair a. Cell. 2023 Oct 26;186(22):4834-4850.e23. doi: 10.1016/j.cell.2023.09.002. Epub 2023 Oct 3. Cell. 2023. PMID: 37794589 Free PMC article.
MDM2 Influences ACE2 Stability and SARS-CoV-2 Uptake.
Emslander Q, Krey K, Hamad S, Maidl S, Oubraham L, Hesse J, Henrici A, Austen K, Mergner J, Grass V, Pichlmair A. Emslander Q, et al. Among authors: pichlmair a. Viruses. 2023 Aug 18;15(8):1763. doi: 10.3390/v15081763. Viruses. 2023. PMID: 37632105 Free PMC article.
Engineered, nucleocytoplasmic shuttling Cas13d enables highly efficient cytosolic RNA targeting.
Gruber C, Krautner L, Bergant V, Grass V, Ma Z, Rheinemann L, Krus A, Reinhardt F, Mazneykova L, Rocha-Hasler M, Truong DJ, Westmeyer GG, Pichlmair A, Ebert G, Giesert F, Wurst W. Gruber C, et al. Among authors: pichlmair a. Cell Discov. 2024 Apr 12;10(1):42. doi: 10.1038/s41421-024-00672-1. Cell Discov. 2024. PMID: 38609360 Free PMC article. No abstract available.
Mucosal IFNλ1 mRNA-based immunomodulation effectively reduces SARS-CoV-2 induced mortality in mice.
Macht A, Huang Y, Reinert LS, Grass V, Lohmer K, Aristizabal Prada ET, Babel E, Semmler A, Zhang W, Wegner A, Lichtenegger-Hartl E, Haas S, Hasenpusch G, Meyer S, Paludan SR, Pichlmair A, Rudolph C, Langenickel T. Macht A, et al. Among authors: pichlmair a. EMBO Rep. 2024 Sep;25(9):3777-3788. doi: 10.1038/s44319-024-00216-4. Epub 2024 Jul 26. EMBO Rep. 2024. PMID: 39060455 Free PMC article.
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