Kay MA - Search Results

1

Minicircle DNA-based gene therapy coupled with immune modulation permits long-term expression of α-L-iduronidase in mice with mucopolysaccharidosis type I.

Osborn MJ, McElmurry RT, Lees CJ, DeFeo AP, Chen ZY, Kay MA, Naldini L, Freeman G, Tolar J, Blazar BR. Osborn MJ, et al. Among authors: kay ma. Mol Ther. 2011 Mar;19(3):450-60. doi: 10.1038/mt.2010.249. Epub 2010 Nov 16. Mol Ther. 2011. PMID: 21081900 Free PMC article.

2

Efficient lentiviral transduction of liver requires cell cycling in vivo.

Park F, Ohashi K, Chiu W, Naldini L, Kay MA. Park F, et al. Among authors: kay ma. Nat Genet. 2000 Jan;24(1):49-52. doi: 10.1038/71673. Nat Genet. 2000. PMID: 10615126

3

Viral vectors for gene therapy: the art of turning infectious agents into vehicles of therapeutics.

Kay MA, Glorioso JC, Naldini L. Kay MA, et al. Nat Med. 2001 Jan;7(1):33-40. doi: 10.1038/83324. Nat Med. 2001. PMID: 11135613 Review.

4

Linear DNAs concatemerize in vivo and result in sustained transgene expression in mouse liver.

Chen ZY, Yant SR, He CY, Meuse L, Shen S, Kay MA. Chen ZY, et al. Among authors: kay ma. Mol Ther. 2001 Mar;3(3):403-10. doi: 10.1006/mthe.2001.0278. Mol Ther. 2001. PMID: 11273783 Free article.

5

Epstein-Barr virus/human vector provides high-level, long-term expression of alpha1-antitrypsin in mice.

Stoll SM, Sclimenti CR, Baba EJ, Meuse L, Kay MA, Calos MP. Stoll SM, et al. Among authors: kay ma. Mol Ther. 2001 Aug;4(2):122-9. doi: 10.1006/mthe.2001.0429. Mol Ther. 2001. PMID: 11482983 Free article.

6

Modified HIV-1 based lentiviral vectors have an effect on viral transduction efficiency and gene expression in vitro and in vivo.

Park F, Kay MA. Park F, et al. Among authors: kay ma. Mol Ther. 2001 Sep;4(3):164-73. doi: 10.1006/mthe.2001.0450. Mol Ther. 2001. PMID: 11545606 Free article.

7

Helper-independent and AAV-ITR-independent chromosomal integration of double-stranded linear DNA vectors in mice.

Nakai H, Montini E, Fuess S, Storm TA, Meuse L, Finegold M, Grompe M, Kay MA. Nakai H, et al. Among authors: kay ma. Mol Ther. 2003 Jan;7(1):101-11. doi: 10.1016/s1525-0016(02)00023-0. Mol Ther. 2003. PMID: 12573623 Free article.

8

Free DNA ends are essential for concatemerization of synthetic double-stranded adeno-associated virus vector genomes transfected into mouse hepatocytes in vivo.

Nakai H, Fuess S, Storm TA, Meuse LA, Kay MA. Nakai H, et al. Among authors: kay ma. Mol Ther. 2003 Jan;7(1):112-21. doi: 10.1016/s1525-0016(02)00034-5. Mol Ther. 2003. PMID: 12573624 Free article.

9

Optimization of cis-acting elements for gene expression from nonviral vectors in vivo.

Ehrhardt A, Peng PD, Xu H, Meuse L, Kay MA. Ehrhardt A, et al. Among authors: kay ma. Hum Gene Ther. 2003 Feb 10;14(3):215-25. doi: 10.1089/10430340360535779. Hum Gene Ther. 2003. PMID: 12639302

10

Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo.

Chen ZY, He CY, Ehrhardt A, Kay MA. Chen ZY, et al. Among authors: kay ma. Mol Ther. 2003 Sep;8(3):495-500. doi: 10.1016/s1525-0016(03)00168-0. Mol Ther. 2003. PMID: 12946323 Free article.

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