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Glucose and weight control in mice with a designed ghrelin O-acyltransferase inhibitor.
Barnett BP, Hwang Y, Taylor MS, Kirchner H, Pfluger PT, Bernard V, Lin YY, Bowers EM, Mukherjee C, Song WJ, Longo PA, Leahy DJ, Hussain MA, Tschöp MH, Boeke JD, Cole PA. Barnett BP, et al. Among authors: hwang y. Science. 2010 Dec 17;330(6011):1689-92. doi: 10.1126/science.1196154. Epub 2010 Nov 18. Science. 2010. PMID: 21097901 Free PMC article.
A selective chemical probe for coenzyme A-requiring enzymes.
Hwang Y, Thompson PR, Wang L, Jiang L, Kelleher NL, Cole PA. Hwang Y, et al. Angew Chem Int Ed Engl. 2007;46(40):7621-4. doi: 10.1002/anie.200702485. Angew Chem Int Ed Engl. 2007. PMID: 17768748 No abstract available.
Electrophilic tuning of the chemoprotective natural product sulforaphane.
Ahn YH, Hwang Y, Liu H, Wang XJ, Zhang Y, Stephenson KK, Boronina TN, Cole RN, Dinkova-Kostova AT, Talalay P, Cole PA. Ahn YH, et al. Among authors: hwang y. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9590-5. doi: 10.1073/pnas.1004104107. Epub 2010 May 3. Proc Natl Acad Sci U S A. 2010. PMID: 20439747 Free PMC article.
Ghrelin O-acyltransferase assays and inhibition.
Taylor MS, Hwang Y, Hsiao PY, Boeke JD, Cole PA. Taylor MS, et al. Among authors: hwang y. Methods Enzymol. 2012;514:205-28. doi: 10.1016/B978-0-12-381272-8.00013-1. Methods Enzymol. 2012. PMID: 22975055 Free PMC article. Review.
Architectural organization of the metabolic regulatory enzyme ghrelin O-acyltransferase.
Taylor MS, Ruch TR, Hsiao PY, Hwang Y, Zhang P, Dai L, Huang CRL, Berndsen CE, Kim MS, Pandey A, Wolberger C, Marmorstein R, Machamer C, Boeke JD, Cole PA. Taylor MS, et al. Among authors: hwang y. J Biol Chem. 2013 Nov 8;288(45):32211-32228. doi: 10.1074/jbc.M113.510313. Epub 2013 Sep 17. J Biol Chem. 2013. PMID: 24045953 Free PMC article.
4,766 results