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IL-27 supports germinal center function by enhancing IL-21 production and the function of T follicular helper cells.
Batten M, Ramamoorthi N, Kljavin NM, Ma CS, Cox JH, Dengler HS, Danilenko DM, Caplazi P, Wong M, Fulcher DA, Cook MC, King C, Tangye SG, de Sauvage FJ, Ghilardi N. Batten M, et al. Among authors: ghilardi n. J Exp Med. 2010 Dec 20;207(13):2895-906. doi: 10.1084/jem.20100064. Epub 2010 Nov 22. J Exp Med. 2010. PMID: 21098093 Free PMC article.
IL-27 promotes T cell-dependent colitis through multiple mechanisms.
Cox JH, Kljavin NM, Ramamoorthi N, Diehl L, Batten M, Ghilardi N. Cox JH, et al. Among authors: ghilardi n. J Exp Med. 2011 Jan 17;208(1):115-23. doi: 10.1084/jem.20100410. Epub 2010 Dec 20. J Exp Med. 2011. PMID: 21173106 Free PMC article.
IL-27 Directly Enhances Germinal Center B Cell Activity and Potentiates Lupus in Sanroque Mice.
Vijayan D, Mohd Redzwan N, Avery DT, Wirasinha RC, Brink R, Walters G, Adelstein S, Kobayashi M, Gray P, Elliott M, Wong M, King C, Vinuesa CG, Ghilardi N, Ma CS, Tangye SG, Batten M. Vijayan D, et al. Among authors: ghilardi n. J Immunol. 2016 Oct 15;197(8):3008-3017. doi: 10.4049/jimmunol.1600652. Epub 2016 Sep 12. J Immunol. 2016. PMID: 27619997
The biology and therapeutic potential of interleukin 27.
Batten M, Ghilardi N. Batten M, et al. Among authors: ghilardi n. J Mol Med (Berl). 2007 Jul;85(7):661-72. doi: 10.1007/s00109-007-0164-7. Epub 2007 Feb 10. J Mol Med (Berl). 2007. PMID: 17294231 Review.
IL-31-IL-31R interactions negatively regulate type 2 inflammation in the lung.
Perrigoue JG, Li J, Zaph C, Goldschmidt M, Scott P, de Sauvage FJ, Pearce EJ, Ghilardi N, Artis D. Perrigoue JG, et al. Among authors: ghilardi n. J Exp Med. 2007 Mar 19;204(3):481-7. doi: 10.1084/jem.20061791. Epub 2007 Mar 12. J Exp Med. 2007. PMID: 17353366 Free PMC article.
Bystanders not so innocent after all.
Batten M, Ghilardi N. Batten M, et al. Among authors: ghilardi n. Immunity. 2012 Jun 29;36(6):901-3. doi: 10.1016/j.immuni.2012.06.001. Immunity. 2012. PMID: 22749349 Free article.
71 results