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5,6-EET is released upon neuronal activity and induces mechanical pain hypersensitivity via TRPA1 on central afferent terminals.
Sisignano M, Park CK, Angioni C, Zhang DD, von Hehn C, Cobos EJ, Ghasemlou N, Xu ZZ, Kumaran V, Lu R, Grant A, Fischer MJ, Schmidtko A, Reeh P, Ji RR, Woolf CJ, Geisslinger G, Scholich K, Brenneis C. Sisignano M, et al. Among authors: zhang dd. J Neurosci. 2012 May 2;32(18):6364-72. doi: 10.1523/JNEUROSCI.5793-11.2012. J Neurosci. 2012. PMID: 22553041 Free PMC article.
Analysis of sphingolipid and prostaglandin synthesis during zymosan-induced inflammation.
Linke B, Schreiber Y, Zhang DD, Pierre S, Coste O, Henke M, Suo J, Fuchs J, Angioni C, Ferreiros-Bouzas N, Geisslinger G, Scholich K. Linke B, et al. Among authors: zhang dd. Prostaglandins Other Lipid Mediat. 2012 Oct;99(1-2):15-23. doi: 10.1016/j.prostaglandins.2012.06.002. Epub 2012 Jun 23. Prostaglandins Other Lipid Mediat. 2012. PMID: 22732087
Targeting CYP2J to reduce paclitaxel-induced peripheral neuropathic pain.
Sisignano M, Angioni C, Park CK, Meyer Dos Santos S, Jordan H, Kuzikov M, Liu D, Zinn S, Hohman SW, Schreiber Y, Zimmer B, Schmidt M, Lu R, Suo J, Zhang DD, Schäfer SM, Hofmann M, Yekkirala AS, de Bruin N, Parnham MJ, Woolf CJ, Ji RR, Scholich K, Geisslinger G. Sisignano M, et al. Among authors: zhang dd. Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):12544-12549. doi: 10.1073/pnas.1613246113. Epub 2016 Oct 17. Proc Natl Acad Sci U S A. 2016. PMID: 27791151 Free PMC article.
914 results