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The inotropic peptide βARKct improves βAR responsiveness in normal and failing cardiomyocytes through G(βγ)-mediated L-type calcium current disinhibition.
Völkers M, Weidenhammer C, Herzog N, Qiu G, Spaich K, Wegner FV, Peppel K, Müller OJ, Schinkel S, Rabinowitz JE, Hippe HJ, Brinks H, Katus HA, Koch WJ, Eckhart AD, Friedrich O, Most P. Völkers M, et al. Among authors: spaich k. Circ Res. 2011 Jan 7;108(1):27-39. doi: 10.1161/CIRCRESAHA.110.225201. Epub 2010 Nov 24. Circ Res. 2011. PMID: 21106943 Free PMC article.
S100A1ct: A Synthetic Peptide Derived From S100A1 Protein Improves Cardiac Performance and Survival in Preclinical Heart Failure Models.
Kehr D, Ritterhoff J, Glaser M, Jarosch L, Salazar RE, Spaich K, Varadi K, Birkenstock J, Egger M, Gao E, Koch WJ, Sauter M, Freichel M, Katus HA, Frey N, Jungmann A, Busch C, Mather PJ, Ruhparwar A, Busch M, Völkers M, Wade RC, Most P. Kehr D, et al. Among authors: spaich k. Circulation. 2024 Nov 21. doi: 10.1161/CIRCULATIONAHA.123.066961. Online ahead of print. Circulation. 2024. PMID: 39569500 Free article.