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Page 1
Glycine and a glycine dehydrogenase (GLDC) SNP as citalopram/escitalopram response biomarkers in depression: pharmacometabolomics-informed pharmacogenomics.
Ji Y, Hebbring S, Zhu H, Jenkins GD, Biernacka J, Snyder K, Drews M, Fiehn O, Zeng Z, Schaid D, Mrazek DA, Kaddurah-Daouk R, Weinshilboum RM. Ji Y, et al. Among authors: fiehn o. Clin Pharmacol Ther. 2011 Jan;89(1):97-104. doi: 10.1038/clpt.2010.250. Epub 2010 Nov 24. Clin Pharmacol Ther. 2011. PMID: 21107318 Free PMC article. Clinical Trial.
Merging pharmacometabolomics with pharmacogenomics using '1000 Genomes' single-nucleotide polymorphism imputation: selective serotonin reuptake inhibitor response pharmacogenomics.
Abo R, Hebbring S, Ji Y, Zhu H, Zeng ZB, Batzler A, Jenkins GD, Biernacka J, Snyder K, Drews M, Fiehn O, Fridley B, Schaid D, Kamatani N, Nakamura Y, Kubo M, Mushiroda T, Kaddurah-Daouk R, Mrazek DA, Weinshilboum RM. Abo R, et al. Among authors: fiehn o. Pharmacogenet Genomics. 2012 Apr;22(4):247-53. doi: 10.1097/FPC.0b013e32835001c9. Pharmacogenet Genomics. 2012. PMID: 22322242 Free PMC article.
Alterations in acylcarnitines, amines, and lipids inform about the mechanism of action of citalopram/escitalopram in major depression.
MahmoudianDehkordi S, Ahmed AT, Bhattacharyya S, Han X, Baillie RA, Arnold M, Skime MK, John-Williams LS, Moseley MA, Thompson JW, Louie G, Riva-Posse P, Craighead WE, McDonald W, Krishnan R, Rush AJ, Frye MA, Dunlop BW, Weinshilboum RM, Kaddurah-Daouk R; Mood Disorders Precision Medicine Consortium (MDPMC). MahmoudianDehkordi S, et al. Transl Psychiatry. 2021 Mar 2;11(1):153. doi: 10.1038/s41398-020-01097-6. Transl Psychiatry. 2021. PMID: 33654056 Free PMC article.
Purine pathway implicated in mechanism of resistance to aspirin therapy: pharmacometabolomics-informed pharmacogenomics.
Yerges-Armstrong LM, Ellero-Simatos S, Georgiades A, Zhu H, Lewis JP, Horenstein RB, Beitelshees AL, Dane A, Reijmers T, Hankemeier T, Fiehn O, Shuldiner AR, Kaddurah-Daouk R. Yerges-Armstrong LM, et al. Among authors: fiehn o. Clin Pharmacol Ther. 2013 Oct;94(4):525-32. doi: 10.1038/clpt.2013.119. Epub 2013 Jun 11. Clin Pharmacol Ther. 2013. PMID: 23839601 Free PMC article. Clinical Trial.
Pharmacometabolomics of response to sertraline and to placebo in major depressive disorder - possible role for methoxyindole pathway.
Zhu H, Bogdanov MB, Boyle SH, Matson W, Sharma S, Matson S, Churchill E, Fiehn O, Rush JA, Krishnan RR, Pickering E, Delnomdedieu M, Kaddurah-Daouk R; Pharmacometabolomics Research Network. Zhu H, et al. Among authors: fiehn o. PLoS One. 2013 Jul 17;8(7):e68283. doi: 10.1371/journal.pone.0068283. Print 2013. PLoS One. 2013. PMID: 23874572 Free PMC article. Clinical Trial.
Pharmacometabolomic mapping of early biochemical changes induced by sertraline and placebo.
Kaddurah-Daouk R, Bogdanov MB, Wikoff WR, Zhu H, Boyle SH, Churchill E, Wang Z, Rush AJ, Krishnan RR, Pickering E, Delnomdedieu M, Fiehn O. Kaddurah-Daouk R, et al. Among authors: fiehn o. Transl Psychiatry. 2013 Jan 22;3(1):e223. doi: 10.1038/tp.2012.142. Transl Psychiatry. 2013. PMID: 23340506 Free PMC article. Clinical Trial.
Pharmacometabolomics reveals racial differences in response to atenolol treatment.
Wikoff WR, Frye RF, Zhu H, Gong Y, Boyle S, Churchill E, Cooper-Dehoff RM, Beitelshees AL, Chapman AB, Fiehn O, Johnson JA, Kaddurah-Daouk R; Pharmacometabolomics Research Network. Wikoff WR, et al. Among authors: fiehn o. PLoS One. 2013;8(3):e57639. doi: 10.1371/journal.pone.0057639. Epub 2013 Mar 11. PLoS One. 2013. PMID: 23536766 Free PMC article.
A Genetic Response Score for Hydrochlorothiazide Use: Insights From Genomics and Metabolomics Integration.
Shahin MH, Gong Y, McDonough CW, Rotroff DM, Beitelshees AL, Garrett TJ, Gums JG, Motsinger-Reif A, Chapman AB, Turner ST, Boerwinkle E, Frye RF, Fiehn O, Cooper-DeHoff RM, Kaddurah-Daouk R, Johnson JA. Shahin MH, et al. Among authors: fiehn o. Hypertension. 2016 Sep;68(3):621-9. doi: 10.1161/HYPERTENSIONAHA.116.07328. Epub 2016 Jul 5. Hypertension. 2016. PMID: 27381900 Free PMC article.
Novel plasma biomarker of atenolol-induced hyperglycemia identified through a metabolomics-genomics integrative approach.
de Oliveira FA, Shahin MH, Gong Y, McDonough CW, Beitelshees AL, Gums JG, Chapman AB, Boerwinkle E, Turner ST, Frye RF, Fiehn O, Kaddurah-Daouk R, Johnson JA, Cooper-DeHoff RM. de Oliveira FA, et al. Among authors: fiehn o. Metabolomics. 2016 Aug;12(8):129. doi: 10.1007/s11306-016-1076-8. Epub 2016 Jul 13. Metabolomics. 2016. PMID: 28217400 Free PMC article.
Metabolomic signatures of drug response phenotypes for ketamine and esketamine in subjects with refractory major depressive disorder: new mechanistic insights for rapid acting antidepressants.
Rotroff DM, Corum DG, Motsinger-Reif A, Fiehn O, Bottrel N, Drevets WC, Singh J, Salvadore G, Kaddurah-Daouk R. Rotroff DM, et al. Among authors: fiehn o. Transl Psychiatry. 2016 Sep 20;6(9):e894. doi: 10.1038/tp.2016.145. Transl Psychiatry. 2016. PMID: 27648916 Free PMC article.
515 results