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Histone deacetylases 1 and 3 but not 2 mediate cytokine-induced beta cell apoptosis in INS-1 cells and dispersed primary islets from rats and are differentially regulated in the islets of type 1 diabetic children.
Lundh M, Christensen DP, Damgaard Nielsen M, Richardson SJ, Dahllöf MS, Skovgaard T, Berthelsen J, Dinarello CA, Stevenazzi A, Mascagni P, Grunnet LG, Morgan NG, Mandrup-Poulsen T. Lundh M, et al. Among authors: christensen dp. Diabetologia. 2012 Sep;55(9):2421-31. doi: 10.1007/s00125-012-2615-0. Epub 2012 Jul 7. Diabetologia. 2012. PMID: 22772764
Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection.
Christensen DP, Gysemans C, Lundh M, Dahllöf MS, Noesgaard D, Schmidt SF, Mandrup S, Birkbak N, Workman CT, Piemonti L, Blaabjerg L, Monzani V, Fossati G, Mascagni P, Paraskevas S, Aikin RA, Billestrup N, Grunnet LG, Dinarello CA, Mathieu C, Mandrup-Poulsen T. Christensen DP, et al. Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1055-9. doi: 10.1073/pnas.1320850111. Epub 2014 Jan 6. Proc Natl Acad Sci U S A. 2014. PMID: 24395784 Free PMC article.
JNK1 protects against glucolipotoxicity-mediated beta-cell apoptosis.
Prause M, Christensen DP, Billestrup N, Mandrup-Poulsen T. Prause M, et al. Among authors: christensen dp. PLoS One. 2014 Jan 24;9(1):e87067. doi: 10.1371/journal.pone.0087067. eCollection 2014. PLoS One. 2014. PMID: 24475223 Free PMC article.
Anti-inflammatory properties of a novel peptide interleukin 1 receptor antagonist.
Klementiev B, Li S, Korshunova I, Dmytriyeva O, Pankratova S, Walmod PS, Kjær LK, Dahllöf MS, Lundh M, Christensen DP, Mandrup-Poulsen T, Bock E, Berezin V. Klementiev B, et al. Among authors: christensen dp. J Neuroinflammation. 2014 Feb 3;11:27. doi: 10.1186/1742-2094-11-27. J Neuroinflammation. 2014. PMID: 24490798 Free PMC article.
30 results