Sáez JC - Search Results

1

Pharmacology of boldine: summary of the field and update on recent advances.

Sáez JC, Burrell JC, Cahill CM, Cullen DK, Devi LA, Gilbert RJ, Graham ZA, Gurvich VJ, Havton LA, Iyengar R, Khanna R, Palermo EF, Siddiq M, Toro CA, Vasquez W, Zhao W, Cardozo CP. Sáez JC, et al. Front Pharmacol. 2024 Sep 13;15:1427147. doi: 10.3389/fphar.2024.1427147. eCollection 2024. Front Pharmacol. 2024. PMID: 39346563 Free PMC article. Review.

2

Pathophysiological role of connexin and pannexin hemichannels in neuromuscular disorders.

Vásquez W, Toro CA, Cardozo CP, Cea LA, Sáez JC. Vásquez W, et al. Among authors: saez jc. J Physiol. 2024 Aug 22. doi: 10.1113/JP286173. Online ahead of print. J Physiol. 2024. PMID: 39173050

3

Acute activation of hemichannels by ethanol leads to Ca²⁺-dependent gliotransmitter release in astrocytes.

Gómez GI, García-Rodríguez C, Marillán JE, Vergara SA, Alvear TF, Farias-Pasten A, Sáez JC, Retamal MA, Rovegno M, Ortiz FC, Orellana JA. Gómez GI, et al. Among authors: saez jc. Front Cell Dev Biol. 2024 Jun 21;12:1422978. doi: 10.3389/fcell.2024.1422978. eCollection 2024. Front Cell Dev Biol. 2024. PMID: 38974144 Free PMC article.

4

Inhibition of astroglial hemichannels prevents synaptic transmission decline during spreading depression.

Tichauer JE, Lira M, Cerpa W, Orellana JA, Sáez JC, Rovegno M. Tichauer JE, et al. Among authors: saez jc. Biol Res. 2024 Jun 12;57(1):39. doi: 10.1186/s40659-024-00519-9. Biol Res. 2024. PMID: 38867288 Free PMC article.

5

Ca²⁺ permeation through C-terminal cleaved, but not full-length human Pannexin1 hemichannels, mediates cell death.

Salgado M, Márquez-Miranda V, Ferrada L, Rojas M, Poblete-Flores G, González-Nilo FD, Ardiles ÁO, Sáez JC. Salgado M, et al. Among authors: saez jc. Proc Natl Acad Sci U S A. 2024 Jun 18;121(25):e2405468121. doi: 10.1073/pnas.2405468121. Epub 2024 Jun 11. Proc Natl Acad Sci U S A. 2024. PMID: 38861601

6

Autocrine activation of P2X7 receptors mediates catecholamine secretion in chromaffin cells.

Maldifassi MC, Guerra-Fernández MJ, Ponce D, Alfonso-Bueno S, Maripillán J, Vielma AH, Báez-Matus X, Marengo FD, Acuña-Castillo C, Sáez JC, Martínez AD, Cárdenas AM. Maldifassi MC, et al. Among authors: saez jc. Br J Pharmacol. 2024 Aug;181(16):2905-2922. doi: 10.1111/bph.16371. Epub 2024 Apr 28. Br J Pharmacol. 2024. PMID: 38679932

7

Enhanced Methodologies for Investigating the Electrophysiological Characteristics of Endogenous Pannexin 1 Intercellular Cell-Cell Channels.

Palacios-Prado N, Vergara T, Sáez JC. Palacios-Prado N, et al. Among authors: saez jc. Methods Mol Biol. 2024;2801:135-145. doi: 10.1007/978-1-0716-3842-2_11. Methods Mol Biol. 2024. PMID: 38578419

8

A Dye Uptake Assay to Measure Large-Pore Channel Activity in Trypanosoma cruzi.

Vega JL, García A, González J, Sáez JC. Vega JL, et al. Among authors: saez jc. Methods Mol Biol. 2024;2801:87-95. doi: 10.1007/978-1-0716-3842-2_7. Methods Mol Biol. 2024. PMID: 38578415

9

Cx43 hemichannels and panx1 channels contribute to ethanol-induced astrocyte dysfunction and damage.

Gómez GI, Alvear TF, Roa DA, Farias-Pasten A, Vergara SA, Mellado LA, Martinez-Araya CJ, Prieto-Villalobos J, García-Rodríguez C, Sánchez N, Sáez JC, Ortíz FC, Orellana JA. Gómez GI, et al. Among authors: saez jc. Biol Res. 2024 Apr 4;57(1):15. doi: 10.1186/s40659-024-00493-2. Biol Res. 2024. PMID: 38576018 Free PMC article.

10

The antiseizure medication valproate increases hemichannel activity found in brain cells, which could worsen disease outcomes.

García-Rodríguez C, Duarte Y, Ardiles ÁO, Sáez JC. García-Rodríguez C, et al. Among authors: saez jc. J Neurochem. 2024 Jun;168(6):1045-1059. doi: 10.1111/jnc.16062. Epub 2024 Jan 30. J Neurochem. 2024. PMID: 38291613

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