Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform.
Taraboulos A, Scott M, Semenov A, Avrahami D, Laszlo L, Prusiner SB.
Taraboulos A, et al. Among authors: scott m.
J Cell Biol. 1995 Apr;129(1):121-32. doi: 10.1083/jcb.129.1.121.
J Cell Biol. 1995.
PMID: 7698979
Free PMC article.
Both CD4PrPC and truncated PrPC without the GPI addition signal (Rogers, M., F. Yehieley, M. Scott, and S. B. Prusiner. 1993. Proc. Natl. Acad. Sci. USA. 90:3182-3186) were poor substrates for PrPSc formation. ...
Both CD4PrPC and truncated PrPC without the GPI addition signal (Rogers, M., F. Yehieley, M. Scott, and S. B. Prusiner. …