Kirby M - Search Results

1

Pharmacokinetics of armodafinil and modafinil after single and multiple doses in patients with excessive sleepiness associated with treated obstructive sleep apnea: a randomized, open-label, crossover study.

Darwish M, Kirby M, D'Andrea DM, Yang R, Hellriegel ET, Robertson P Jr. Darwish M, et al. Among authors: kirby m. Clin Ther. 2010 Nov;32(12):2074-87. doi: 10.1016/j.clinthera.2010.11.009. Clin Ther. 2010. PMID: 21118743 Clinical Trial.

2

Pharmacokinetic properties of fentanyl effervescent buccal tablets: a phase I, open-label, crossover study of single-dose 100, 200, 400, and 800 microg in healthy adult volunteers.

Darwish M, Kirby M, Robertson P Jr, Tracewell W, Jiang JG. Darwish M, et al. Among authors: kirby m. Clin Ther. 2006 May;28(5):707-14. doi: 10.1016/j.clinthera.2006.05.015. Clin Ther. 2006. PMID: 16861092 Clinical Trial.

3

Relative bioavailability of the fentanyl effervescent buccal tablet (FEBT) 1,080 pg versus oral transmucosal fentanyl citrate 1,600 pg and dose proportionality of FEBT 270 to 1,300 microg: a single-dose, randomized, open-label, three-period study in healthy adult volunteers.

Darwish M, Tempero K, Kirby M, Thompson J. Darwish M, et al. Among authors: kirby m. Clin Ther. 2006 May;28(5):715-24. doi: 10.1016/j.clinthera.2006.05.016. Clin Ther. 2006. PMID: 16861093 Clinical Trial.

4

Comparison of equivalent doses of fentanyl buccal tablets and arteriovenous differences in fentanyl pharmacokinetics.

Darwish M, Kirby M, Robertson P Jr, Hellriegel E, Jiang JG. Darwish M, et al. Among authors: kirby m. Clin Pharmacokinet. 2006;45(8):843-50. doi: 10.2165/00003088-200645080-00006. Clin Pharmacokinet. 2006. PMID: 16884321 Clinical Trial.

5

Single-dose and steady-state pharmacokinetics of fentanyl buccal tablet in healthy volunteers.

Darwish M, Kirby M, Robertson P Jr, Hellriegel E, Jiang JG. Darwish M, et al. Among authors: kirby m. J Clin Pharmacol. 2007 Jan;47(1):56-63. doi: 10.1177/0091270006294129. J Clin Pharmacol. 2007. PMID: 17192502 Clinical Trial.

6

Absolute and relative bioavailability of fentanyl buccal tablet and oral transmucosal fentanyl citrate.

Darwish M, Kirby M, Robertson P Jr, Tracewell W, Jiang JG. Darwish M, et al. Among authors: kirby m. J Clin Pharmacol. 2007 Mar;47(3):343-50. doi: 10.1177/0091270006297749. J Clin Pharmacol. 2007. PMID: 17322146 Clinical Trial.

7

Interaction profile of armodafinil with medications metabolized by cytochrome P450 enzymes 1A2, 3A4 and 2C19 in healthy subjects.

Darwish M, Kirby M, Robertson P Jr, Hellriegel ET. Darwish M, et al. Among authors: kirby m. Clin Pharmacokinet. 2008;47(1):61-74. doi: 10.2165/00003088-200847010-00006. Clin Pharmacokinet. 2008. PMID: 18076219

8

Pharmacokinetic profile of armodafinil in healthy subjects: pooled analysis of data from three randomized studies.

Darwish M, Kirby M, Hellriegel ET, Yang R, Robertson P Jr. Darwish M, et al. Among authors: kirby m. Clin Drug Investig. 2009;29(2):87-100. doi: 10.2165/0044011-200929020-00003. Clin Drug Investig. 2009. PMID: 19133704

9

Comparison of steady-state plasma concentrations of armodafinil and modafinil late in the day following morning administration: post hoc analysis of two randomized, double-blind, placebo-controlled, multiple-dose studies in healthy male subjects.

Darwish M, Kirby M, Hellriegel ET. Darwish M, et al. Among authors: kirby m. Clin Drug Investig. 2009;29(9):601-12. doi: 10.2165/11317740-000000000-00000. Clin Drug Investig. 2009. PMID: 19663522

10

Armodafinil and modafinil have substantially different pharmacokinetic profiles despite having the same terminal half-lives: analysis of data from three randomized, single-dose, pharmacokinetic studies.

Darwish M, Kirby M, Hellriegel ET, Robertson P Jr. Darwish M, et al. Among authors: kirby m. Clin Drug Investig. 2009;29(9):613-23. doi: 10.2165/11315280-000000000-00000. Clin Drug Investig. 2009. PMID: 19663523

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