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Synthesis and pharmacological evaluation of N-(3-(1H-indol-4-yl)-5-(2-methoxyisonicotinoyl)phenyl)methanesulfonamide (LP-261), a potent antimitotic agent.
Shetty RS, Lee Y, Liu B, Husain A, Joseph RW, Lu Y, Nelson D, Mihelcic J, Chao W, Moffett KK, Schumacher A, Flubacher D, Stojanovic A, Bukhtiyarova M, Williams K, Lee KJ, Ochman AR, Saporito MS, Moore WR, Flynn GA, Dorsey BD, Springman EB, Fujimoto T, Kelly MJ. Shetty RS, et al. Among authors: fujimoto t. J Med Chem. 2011 Jan 13;54(1):179-200. doi: 10.1021/jm100659v. Epub 2010 Dec 2. J Med Chem. 2011. PMID: 21126027
Two classes of p38alpha MAP kinase inhibitors having a common diphenylether core but exhibiting divergent binding modes.
Michelotti EL, Moffett KK, Nguyen D, Kelly MJ, Shetty R, Chai X, Northrop K, Namboodiri V, Campbell B, Flynn GA, Fujimoto T, Hollinger FP, Bukhtiyarova M, Springman EB, Karpusas M. Michelotti EL, et al. Among authors: fujimoto t. Bioorg Med Chem Lett. 2005 Dec 1;15(23):5274-9. doi: 10.1016/j.bmcl.2005.08.038. Epub 2005 Sep 19. Bioorg Med Chem Lett. 2005. PMID: 16169718
Discovery of a novel class of non-ATP site DFG-out state p38 inhibitors utilizing computationally assisted virtual fragment-based drug design (vFBDD).
Moffett K, Konteatis Z, Nguyen D, Shetty R, Ludington J, Fujimoto T, Lee KJ, Chai X, Namboodiri H, Karpusas M, Dorsey B, Guarnieri F, Bukhtiyarova M, Springman E, Michelotti E. Moffett K, et al. Among authors: fujimoto t. Bioorg Med Chem Lett. 2011 Dec 1;21(23):7155-65. doi: 10.1016/j.bmcl.2011.09.078. Epub 2011 Sep 28. Bioorg Med Chem Lett. 2011. PMID: 22014550
Impact of adipocytes on ultrasound evaluation of parathyroid adenomas.
Fujimoto T, Hirokawa M, Suzuki A, Oshita M, Yamaoka H, Fujishima M, Onoda N, Miyauchi A, Akamizu T. Fujimoto T, et al. J Med Ultrason (2001). 2024 Dec 28. doi: 10.1007/s10396-024-01511-2. Online ahead of print. J Med Ultrason (2001). 2024. PMID: 39731664
2,379 results