Shim CK - Search Results

1

Pharmacokinetics and first-pass elimination of metoprolol in rats: contribution of intestinal first-pass extraction to low bioavailability of metoprolol.

Yoon IS, Choi MK, Kim JS, Shim CK, Chung SJ, Kim DD. Yoon IS, et al. Among authors: shim ck. Xenobiotica. 2011 Mar;41(3):243-51. doi: 10.3109/00498254.2010.538090. Epub 2010 Dec 3. Xenobiotica. 2011. PMID: 21128757

2

Comparison of pharmacokinetics of loxoprofen and its active metabolites after an intravenous, intramuscular, and oral administration of loxoprofen in rats: evidence for extrahepatic metabolism.

Koo TS, Kim DH, Ahn SH, Kim KP, Kim IW, Seo SY, Suh YG, Kim DD, Shim CK, Chung SJ. Koo TS, et al. Among authors: shim ck. J Pharm Sci. 2005 Oct;94(10):2187-97. doi: 10.1002/jps.20451. J Pharm Sci. 2005. PMID: 16136574

3

Dose dependency in the oral bioavailability of an organic cation model, tributylmethyl ammonium (TBuMA), in rats: association with the saturation of efflux by the P-gp system on the apical membrane of the intestinal epithelium.

Kim MK, Han L, Choi MK, Han YH, Kim DD, Chung SJ, Shim CK. Kim MK, et al. Among authors: shim ck. J Pharm Sci. 2005 Dec;94(12):2644-55. doi: 10.1002/jps.20456. J Pharm Sci. 2005. PMID: 16258993

4

Altered pharmacokinetics of daunorubicin in rats with CCl4-induced hepatic injury.

Choi MK, Song IS, Kim DD, Chung SJ, Shim CK. Choi MK, et al. Among authors: shim ck. J Pharm Pharm Sci. 2007;10(4):443-54. doi: 10.18433/j3mw28. J Pharm Pharm Sci. 2007. PMID: 18261366 Free article.

5

Contribution of a significant first-pass effect of dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylene dioxybiphenyl-2,2'-dicarboxylate in the liver to its poor bioavailability in rats.

Yu KH, Lee YR, Ahn SH, Kim DD, Shim CK, Chung SJ. Yu KH, et al. Among authors: shim ck. J Pharm Pharmacol. 2009 Sep;61(9):1197-203. doi: 10.1211/jpp/61.09.0009. J Pharm Pharmacol. 2009. PMID: 19703369

6

Docetaxel microemulsion for enhanced oral bioavailability: preparation and in vitro and in vivo evaluation.

Yin YM, Cui FD, Mu CF, Choi MK, Kim JS, Chung SJ, Shim CK, Kim DD. Yin YM, et al. Among authors: shim ck. J Control Release. 2009 Dec 3;140(2):86-94. doi: 10.1016/j.jconrel.2009.08.015. Epub 2009 Aug 23. J Control Release. 2009. PMID: 19709639

7

Physiologically based pharmacokinetic modeling of SNU-0039, an anti-Alzheimer's agent, in rats.

Lee KR, Chae YJ, Maeng HJ, Lee J, Kim DD, Chong S, Shim CK, Chung SJ. Lee KR, et al. Among authors: shim ck. J Pharmacokinet Pharmacodyn. 2011 Oct;38(5):637-51. doi: 10.1007/s10928-011-9212-6. Epub 2011 Aug 25. J Pharmacokinet Pharmacodyn. 2011. PMID: 21866408

8

Enhanced intracellular accumulation of a non-nucleoside anti-cancer agent via increased uptake of its valine ester prodrug through amino acid transporters.

Kwak EY, Shim WS, Chang JE, Chong S, Kim DD, Chung SJ, Shim CK. Kwak EY, et al. Among authors: shim ck, shim ws. Xenobiotica. 2012 Jul;42(7):603-13. doi: 10.3109/00498254.2011.646339. Epub 2012 Jan 10. Xenobiotica. 2012. PMID: 22233275

9

Saturable sinusoidal uptake is rate-determining process in hepatic elimination of docetaxel in rats.

Yoon I, Han S, Choi YH, Kang HE, Cho HJ, Kim JS, Shim CK, Chung SJ, Chong S, Kim DD. Yoon I, et al. Among authors: shim ck. Xenobiotica. 2012 Nov;42(11):1110-9. doi: 10.3109/00498254.2012.700139. Epub 2012 Jul 2. Xenobiotica. 2012. PMID: 22747239

10

Transport of gemifloxacin, a 4th generation quinolone antibiotic, in the Caco-2 and engineered MDCKII cells, and potential involvement of efflux transporters in the intestinal absorption of the drug.

Jin HE, Song B, Kim SB, Shim WS, Kim DD, Chong S, Chung SJ, Shim CK. Jin HE, et al. Among authors: shim ck, shim ws. Xenobiotica. 2013 Apr;43(4):355-67. doi: 10.3109/00498254.2012.720740. Epub 2012 Sep 28. Xenobiotica. 2013. PMID: 23020787

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