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The CEBPA gene is down-regulated in acute promyelocytic leukemia and its upstream promoter, but not the core promoter, is highly methylated.
Santana-Lemos BA, de Lima Lange AP, de Lira Benício MT, José TD, Lucena-Araújo AR, Krause A, Thomé CH, Rego EM. Santana-Lemos BA, et al. Among authors: de lima lange ap. Haematologica. 2011 Apr;96(4):617-20. doi: 10.3324/haematol.2010.028365. Epub 2010 Dec 6. Haematologica. 2011. PMID: 21134977 Free PMC article.