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JTT-130, a novel intestine-specific inhibitor of microsomal triglyceride transfer protein, suppresses food intake and gastric emptying with the elevation of plasma peptide YY and glucagon-like peptide-1 in a dietary fat-dependent manner.
Hata T, Mera Y, Ishii Y, Tadaki H, Tomimoto D, Kuroki Y, Kawai T, Ohta T, Kakutani M. Hata T, et al. J Pharmacol Exp Ther. 2011 Mar;336(3):850-6. doi: 10.1124/jpet.110.176560. Epub 2010 Dec 7. J Pharmacol Exp Ther. 2011. PMID: 21139060
Pharmacological characterization of diethyl-2-({3-dimethylcarbamoyl-4-[(4'-trifluoromethylbiphenyl-2-carbonyl)amino]phenyl}acetyloxymethyl)-2-phenylmalonate (JTT-130), an intestine-specific inhibitor of microsomal triglyceride transfer protein.
Mera Y, Odani N, Kawai T, Hata T, Suzuki M, Hagiwara A, Katsushima T, Kakutani M. Mera Y, et al. Among authors: hata t. J Pharmacol Exp Ther. 2011 Feb;336(2):321-7. doi: 10.1124/jpet.110.173807. Epub 2010 Oct 25. J Pharmacol Exp Ther. 2011. PMID: 20974698
JTP-117968, a novel selective glucocorticoid receptor modulator, exhibits significant anti-inflammatory effect while maintaining bone mineral density in mice.
Kurimoto T, Tamai I, Nakagawa T, Miyai A, Yamamoto Y, Kosugi Y, Deai K, Hata T, Ohta T, Matsushita M, Yamada T. Kurimoto T, et al. Among authors: hata t. Eur J Pharmacol. 2021 Mar 15;895:173880. doi: 10.1016/j.ejphar.2021.173880. Epub 2021 Jan 18. Eur J Pharmacol. 2021. PMID: 33476654 Free article.
2,154 results