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Chromosomal instability determines taxane response.
Swanton C, Nicke B, Schuett M, Eklund AC, Ng C, Li Q, Hardcastle T, Lee A, Roy R, East P, Kschischo M, Endesfelder D, Wylie P, Kim SN, Chen JG, Howell M, Ried T, Habermann JK, Auer G, Brenton JD, Szallasi Z, Downward J. Swanton C, et al. Proc Natl Acad Sci U S A. 2009 May 26;106(21):8671-6. doi: 10.1073/pnas.0811835106. Epub 2009 May 19. Proc Natl Acad Sci U S A. 2009. PMID: 19458043 Free PMC article.
Assessment of an RNA interference screen-derived mitotic and ceramide pathway metagene as a predictor of response to neoadjuvant paclitaxel for primary triple-negative breast cancer: a retrospective analysis of five clinical trials.
Juul N, Szallasi Z, Eklund AC, Li Q, Burrell RA, Gerlinger M, Valero V, Andreopoulou E, Esteva FJ, Symmans WF, Desmedt C, Haibe-Kains B, Sotiriou C, Pusztai L, Swanton C. Juul N, et al. Among authors: swanton c. Lancet Oncol. 2010 Apr;11(4):358-65. doi: 10.1016/S1470-2045(10)70018-8. Epub 2010 Feb 26. Lancet Oncol. 2010. PMID: 20189874 Free article.
Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets.
Swanton C, Larkin JM, Gerlinger M, Eklund AC, Howell M, Stamp G, Downward J, Gore M, Futreal PA, Escudier B, Andre F, Albiges L, Beuselinck B, Oudard S, Hoffmann J, Gyorffy B, Torrance CJ, Boehme KA, Volkmer H, Toschi L, Nicke B, Beck M, Szallasi Z. Swanton C, et al. Genome Med. 2010 Aug 11;2(8):53. doi: 10.1186/gm174. Genome Med. 2010. PMID: 20701793 Free PMC article.
Relationship of extreme chromosomal instability with long-term survival in a retrospective analysis of primary breast cancer.
Roylance R, Endesfelder D, Gorman P, Burrell RA, Sander J, Tomlinson I, Hanby AM, Speirs V, Richardson AL, Birkbak NJ, Eklund AC, Downward J, Kschischo M, Szallasi Z, Swanton C. Roylance R, et al. Among authors: swanton c. Cancer Epidemiol Biomarkers Prev. 2011 Oct;20(10):2183-94. doi: 10.1158/1055-9965.EPI-11-0343. Epub 2011 Jul 22. Cancer Epidemiol Biomarkers Prev. 2011. PMID: 21784954 Free PMC article.
463 results