Griffin PR - Search Results

1

A combined ligand- and structure-based virtual screening protocol identifies submicromolar PPARγ partial agonists.

Vidović D, Busby SA, Griffin PR, Schürer SC. Vidović D, et al. Among authors: griffin pr. ChemMedChem. 2011 Jan 3;6(1):94-103. doi: 10.1002/cmdc.201000428. ChemMedChem. 2011. PMID: 21162086 Free PMC article.

2

Probing protein ligand interactions by automated hydrogen/deuterium exchange mass spectrometry.

Chalmers MJ, Busby SA, Pascal BD, He Y, Hendrickson CL, Marshall AG, Griffin PR. Chalmers MJ, et al. Among authors: griffin pr. Anal Chem. 2006 Feb 15;78(4):1005-14. doi: 10.1021/ac051294f. Anal Chem. 2006. PMID: 16478090

3

Structural mobility in human manganese superoxide dismutase.

Quint P, Ayala I, Busby SA, Chalmers MJ, Griffin PR, Rocca J, Nick HS, Silverman DN. Quint P, et al. Among authors: griffin pr. Biochemistry. 2006 Jul 11;45(27):8209-15. doi: 10.1021/bi0606288. Biochemistry. 2006. PMID: 16819819

4

The Deuterator: software for the determination of backbone amide deuterium levels from H/D exchange MS data.

Pascal BD, Chalmers MJ, Busby SA, Mader CC, Southern MR, Tsinoremas NF, Griffin PR. Pascal BD, et al. Among authors: griffin pr. BMC Bioinformatics. 2007 May 16;8:156. doi: 10.1186/1471-2105-8-156. BMC Bioinformatics. 2007. PMID: 17506883 Free PMC article.

5

A two-stage differential hydrogen deuterium exchange method for the rapid characterization of protein/ligand interactions.

Chalmers MJ, Busby SA, Pascal BD, Southern MR, Griffin PR. Chalmers MJ, et al. Among authors: griffin pr. J Biomol Tech. 2007 Sep;18(4):194-204. J Biomol Tech. 2007. PMID: 17916792 Free PMC article.

6

Partial agonists activate PPARgamma using a helix 12 independent mechanism.

Bruning JB, Chalmers MJ, Prasad S, Busby SA, Kamenecka TM, He Y, Nettles KW, Griffin PR. Bruning JB, et al. Among authors: griffin pr. Structure. 2007 Oct;15(10):1258-71. doi: 10.1016/j.str.2007.07.014. Structure. 2007. PMID: 17937915 Free article.

7

HD desktop: an integrated platform for the analysis and visualization of H/D exchange data.

Pascal BD, Chalmers MJ, Busby SA, Griffin PR. Pascal BD, et al. Among authors: griffin pr. J Am Soc Mass Spectrom. 2009 Apr;20(4):601-10. doi: 10.1016/j.jasms.2008.11.019. Epub 2008 Dec 6. J Am Soc Mass Spectrom. 2009. PMID: 19135386 Free PMC article.

8

Identification of specific hemopexin-like domain residues that facilitate matrix metalloproteinase collagenolytic activity.

Lauer-Fields JL, Chalmers MJ, Busby SA, Minond D, Griffin PR, Fields GB. Lauer-Fields JL, et al. Among authors: griffin pr. J Biol Chem. 2009 Sep 4;284(36):24017-24. doi: 10.1074/jbc.M109.016873. Epub 2009 Jul 1. J Biol Chem. 2009. PMID: 19574232 Free PMC article.

9

Apo-human carbonic anhydrase II revisited: implications of the loss of a metal in protein structure, stability, and solvent network.

Avvaru BS, Busby SA, Chalmers MJ, Griffin PR, Venkatakrishnan B, Agbandje-McKenna M, Silverman DN, McKenna R. Avvaru BS, et al. Among authors: griffin pr. Biochemistry. 2009 Aug 11;48(31):7365-72. doi: 10.1021/bi9007512. Biochemistry. 2009. PMID: 19583303 Free PMC article.

10

The benzenesulfoamide T0901317 [N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] is a novel retinoic acid receptor-related orphan receptor-alpha/gamma inverse agonist.

Kumar N, Solt LA, Conkright JJ, Wang Y, Istrate MA, Busby SA, Garcia-Ordonez RD, Burris TP, Griffin PR. Kumar N, et al. Among authors: griffin pr. Mol Pharmacol. 2010 Feb;77(2):228-36. doi: 10.1124/mol.109.060905. Epub 2009 Nov 3. Mol Pharmacol. 2010. PMID: 19887649 Free PMC article.

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