Milhous WK - Search Results

1

In vitro efficacy of 7-benzylamino-1-isoquinolinamines against Plasmodium falciparum related to the efficacy of chalcones.

Gutteridge CE, Hoffman MM, Bhattacharjee AK, Milhous WK, Gerena L. Gutteridge CE, et al. Among authors: milhous wk. Bioorg Med Chem Lett. 2011 Jan 15;21(2):786-9. doi: 10.1016/j.bmcl.2010.11.099. Epub 2010 Nov 26. Bioorg Med Chem Lett. 2011. PMID: 21168330

2

Design, synthesis, and evaluation of new chemosensitizers in multi-drug-resistant Plasmodium falciparum.

Guan J, Kyle DE, Gerena L, Zhang Q, Milhous WK, Lin AJ. Guan J, et al. Among authors: milhous wk. J Med Chem. 2002 Jun 20;45(13):2741-8. doi: 10.1021/jm010549o. J Med Chem. 2002. PMID: 12061877

3

Efficacy of proton pump inhibitor drugs against Plasmodium falciparum in vitro and their probable pharmacophores.

Riel MA, Kyle DE, Bhattacharjee AK, Milhous WK. Riel MA, et al. Among authors: milhous wk. Antimicrob Agents Chemother. 2002 Aug;46(8):2627-32. doi: 10.1128/AAC.46.8.2627-2632.2002. Antimicrob Agents Chemother. 2002. PMID: 12121943 Free PMC article.

4

Mixed steroidal 1,2,4,5-tetraoxanes: antimalarial and antimycobacterial activity.

Solaja BA, Terzić N, Pocsfalvi G, Gerena L, Tinant B, Opsenica D, Milhous WK. Solaja BA, et al. Among authors: milhous wk. J Med Chem. 2002 Aug 1;45(16):3331-6. doi: 10.1021/jm020891g. J Med Chem. 2002. PMID: 12139444

5

Structure-activity relationship study of antimalarial indolo [2,1-b]quinazoline-6,12-diones (tryptanthrins). Three dimensional pharmacophore modeling and identification of new antimalarial candidates.

Bhattacharjee AK, Hartell MG, Nichols DA, Hicks RP, Stanton B, van Hamont JE, Milhous WK. Bhattacharjee AK, et al. Among authors: milhous wk. Eur J Med Chem. 2004 Jan;39(1):59-67. doi: 10.1016/j.ejmech.2003.10.004. Eur J Med Chem. 2004. PMID: 14987834

6

Bisquinolines. 1. N,N-bis(7-chloroquinolin-4-yl)alkanediamines with potential against chloroquine-resistant malaria.

Vennerstrom JL, Ellis WY, Ager AL Jr, Andersen SL, Gerena L, Milhous WK. Vennerstrom JL, et al. Among authors: milhous wk. J Med Chem. 1992 May 29;35(11):2129-34. doi: 10.1021/jm00089a025. J Med Chem. 1992. PMID: 1597862

7

Extraordinarily potent antimalarial compounds: new, structurally simple, easily synthesized, tricyclic 1,2,4-trioxanes.

Posner GH, Oh CH, Gerena L, Milhous WK. Posner GH, et al. Among authors: milhous wk. J Med Chem. 1992 Jun 26;35(13):2459-67. doi: 10.1021/jm00091a014. J Med Chem. 1992. PMID: 1619620

8

Mechanism-based design, synthesis, and in vitro antimalarial testing of new 4-methylated trioxanes structurally related to artemisinin: the importance of a carbon-centered radical for antimalarial activity.

Posner GH, Oh CH, Wang D, Gerena L, Milhous WK, Meshnick SR, Asawamahasadka W. Posner GH, et al. Among authors: milhous wk. J Med Chem. 1994 Apr 29;37(9):1256-8. doi: 10.1021/jm00035a003. J Med Chem. 1994. PMID: 8176702 No abstract available.

9

Fluoxetine hydrochloride enhances in vitro susceptibility to chloroquine in resistant Plasmodium falciparum.

Gerena L, Bass GT Sr, Kyle DE, Oduola AM, Milhous WK, Martin RK. Gerena L, et al. Among authors: milhous wk. Antimicrob Agents Chemother. 1992 Dec;36(12):2761-5. doi: 10.1128/AAC.36.12.2761. Antimicrob Agents Chemother. 1992. PMID: 1482144 Free PMC article.

10

Dispiro-1,2,4,5-tetraoxanes: a new class of antimalarial peroxides.

Vennerstrom JL, Fu HN, Ellis WY, Ager AL Jr, Wood JK, Andersen SL, Gerena L, Milhous WK. Vennerstrom JL, et al. Among authors: milhous wk. J Med Chem. 1992 Aug 7;35(16):3023-7. doi: 10.1021/jm00094a015. J Med Chem. 1992. PMID: 1501229

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