Zu T - Search Results

1

Non-ATG-initiated translation directed by microsatellite expansions.

Zu T, Gibbens B, Doty NS, Gomes-Pereira M, Huguet A, Stone MD, Margolis J, Peterson M, Markowski TW, Ingram MA, Nan Z, Forster C, Low WC, Schoser B, Somia NV, Clark HB, Schmechel S, Bitterman PB, Gourdon G, Swanson MS, Moseley M, Ranum LP. Zu T, et al. Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):260-5. doi: 10.1073/pnas.1013343108. Epub 2010 Dec 20. Proc Natl Acad Sci U S A. 2011. PMID: 21173221 Free PMC article.

2

Bidirectional expression of CUG and CAG expansion transcripts and intranuclear polyglutamine inclusions in spinocerebellar ataxia type 8.

Moseley ML, Zu T, Ikeda Y, Gao W, Mosemiller AK, Daughters RS, Chen G, Weatherspoon MR, Clark HB, Ebner TJ, Day JW, Ranum LP. Moseley ML, et al. Among authors: zu t. Nat Genet. 2006 Jul;38(7):758-69. doi: 10.1038/ng1827. Epub 2006 Jun 25. Nat Genet. 2006. PMID: 16804541

3

Antisense RNA sequences modulating the ataxin-1 message: molecular model of gene therapy for spinocerebellar ataxia type 1, a dominant-acting unstable trinucleotide repeat disease.

Gao Y, Zu T, Low WC, Orr HT, McIvor RS. Gao Y, et al. Among authors: zu t. Cell Transplant. 2008;17(7):723-34. doi: 10.3727/096368908786516729. Cell Transplant. 2008. PMID: 19044200 Free article.

4

RAN Translation Regulated by Muscleblind Proteins in Myotonic Dystrophy Type 2.

Zu T, Cleary JD, Liu Y, Bañez-Coronel M, Bubenik JL, Ayhan F, Ashizawa T, Xia G, Clark HB, Yachnis AT, Swanson MS, Ranum LPW. Zu T, et al. Neuron. 2017 Sep 13;95(6):1292-1305.e5. doi: 10.1016/j.neuron.2017.08.039. Neuron. 2017. PMID: 28910618 Free PMC article.

5

Repeat-Associated Non-ATG Translation in Neurological Diseases.

Zu T, Pattamatta A, Ranum LPW. Zu T, et al. Cold Spring Harb Perspect Biol. 2018 Dec 3;10(12):a033019. doi: 10.1101/cshperspect.a033019. Cold Spring Harb Perspect Biol. 2018. PMID: 29891563 Free PMC article. Review.

6

Targeted deletion of a single Sca8 ataxia locus allele in mice causes abnormal gait, progressive loss of motor coordination, and Purkinje cell dendritic deficits.

He Y, Zu T, Benzow KA, Orr HT, Clark HB, Koob MD. He Y, et al. Among authors: zu t. J Neurosci. 2006 Sep 27;26(39):9975-82. doi: 10.1523/JNEUROSCI.2595-06.2006. J Neurosci. 2006. PMID: 17005861 Free PMC article.

7

Metformin inhibits RAN translation through PKR pathway and mitigates disease in C9orf72 ALS/FTD mice.

Zu T, Guo S, Bardhi O, Ryskamp DA, Li J, Khoramian Tusi S, Engelbrecht A, Klippel K, Chakrabarty P, Nguyen L, Golde TE, Sonenberg N, Ranum LPW. Zu T, et al. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18591-18599. doi: 10.1073/pnas.2005748117. Epub 2020 Jul 20. Proc Natl Acad Sci U S A. 2020. PMID: 32690681 Free PMC article.

8

RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia.

Zu T, Liu Y, Bañez-Coronel M, Reid T, Pletnikova O, Lewis J, Miller TM, Harms MB, Falchook AE, Subramony SH, Ostrow LW, Rothstein JD, Troncoso JC, Ranum LP. Zu T, et al. Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):E4968-77. doi: 10.1073/pnas.1315438110. Epub 2013 Nov 18. Proc Natl Acad Sci U S A. 2013. PMID: 24248382 Free PMC article. Clinical Trial.

9

Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice.

Emamian ES, Kaytor MD, Duvick LA, Zu T, Tousey SK, Zoghbi HY, Clark HB, Orr HT. Emamian ES, et al. Among authors: zu t. Neuron. 2003 May 8;38(3):375-87. doi: 10.1016/s0896-6273(03)00258-7. Neuron. 2003. PMID: 12741986 Free article.

10

SCA8 RAN polySer protein preferentially accumulates in white matter regions and is regulated by eIF3F.

Ayhan F, Perez BA, Shorrock HK, Zu T, Banez-Coronel M, Reid T, Furuya H, Clark HB, Troncoso JC, Ross CA, Subramony SH, Ashizawa T, Wang ET, Yachnis AT, Ranum LP. Ayhan F, et al. Among authors: zu t. EMBO J. 2018 Oct 1;37(19):e99023. doi: 10.15252/embj.201899023. Epub 2018 Sep 11. EMBO J. 2018. PMID: 30206144 Free PMC article.

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