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Page 1
Oncostatin M-enhanced vascular endothelial growth factor expression in human vascular smooth muscle cells involves PI3K-, p38 MAPK-, Erk1/2- and STAT1/STAT3-dependent pathways and is attenuated by interferon-γ.
Demyanets S, Kaun C, Rychli K, Pfaffenberger S, Kastl SP, Hohensinner PJ, Rega G, Katsaros KM, Afonyushkin T, Bochkov VN, Paireder M, Huk I, Maurer G, Huber K, Wojta J. Demyanets S, et al. Among authors: bochkov vn. Basic Res Cardiol. 2011 Mar;106(2):217-31. doi: 10.1007/s00395-010-0141-0. Epub 2010 Dec 21. Basic Res Cardiol. 2011. PMID: 21174212
The estrogen metabolite 17beta-dihydroequilenin counteracts interleukin-1alpha induced expression of inflammatory mediators in human endothelial cells in vitro via NF-kappaB pathway.
Demyanets S, Pfaffenberger S, Kaun C, Rega G, Speidl WS, Kastl SP, Weiss TW, Hohensinner PJ, Dietrich W, Tschugguel W, Bochkov VN, Awad EM, Maurer G, Huber K, Wojta J. Demyanets S, et al. Among authors: bochkov vn. Thromb Haemost. 2006 Jan;95(1):107-16. Thromb Haemost. 2006. PMID: 16543969
Oxidized phospholipids stimulate angiogenesis via autocrine mechanisms, implicating a novel role for lipid oxidation in the evolution of atherosclerotic lesions.
Bochkov VN, Philippova M, Oskolkova O, Kadl A, Furnkranz A, Karabeg E, Afonyushkin T, Gruber F, Breuss J, Minchenko A, Mechtcheriakova D, Hohensinner P, Rychli K, Wojta J, Resink T, Erne P, Binder BR, Leitinger N. Bochkov VN, et al. Circ Res. 2006 Oct 13;99(8):900-8. doi: 10.1161/01.RES.0000245485.04489.ee. Epub 2006 Sep 14. Circ Res. 2006. PMID: 16973904
The inflammatory cytokine oncostatin M induces PAI-1 in human vascular smooth muscle cells in vitro via PI 3-kinase and ERK1/2-dependent pathways.
Demyanets S, Kaun C, Rychli K, Rega G, Pfaffenberger S, Afonyushkin T, Bochkov VN, Maurer G, Huber K, Wojta J. Demyanets S, et al. Among authors: bochkov vn. Am J Physiol Heart Circ Physiol. 2007 Sep;293(3):H1962-8. doi: 10.1152/ajpheart.01366.2006. Epub 2007 Jun 29. Am J Physiol Heart Circ Physiol. 2007. PMID: 17604327 Free article.
In human macrophages the complement component C5a induces the expression of oncostatin M via AP-1 activation.
Kastl SP, Speidl WS, Kaun C, Katsaros KM, Rega G, Afonyushkin T, Bochkov VN, Valent P, Assadian A, Hagmueller GW, Hoeth M, de Martin R, Ma Y, Maurer G, Huber K, Wojta J. Kastl SP, et al. Among authors: bochkov vn. Arterioscler Thromb Vasc Biol. 2008 Mar;28(3):498-503. doi: 10.1161/ATVBAHA.107.160580. Epub 2008 Jan 10. Arterioscler Thromb Vasc Biol. 2008. PMID: 18187666
ATF4-dependent transcription is a key mechanism in VEGF up-regulation by oxidized phospholipids: critical role of oxidized sn-2 residues in activation of unfolded protein response.
Oskolkova OV, Afonyushkin T, Leitner A, von Schlieffen E, Gargalovic PS, Lusis AJ, Binder BR, Bochkov VN. Oskolkova OV, et al. Among authors: bochkov vn. Blood. 2008 Jul 15;112(2):330-9. doi: 10.1182/blood-2007-09-112870. Epub 2008 May 1. Blood. 2008. PMID: 18451308 Free PMC article.
Oxidized phospholipids regulate expression of ATF4 and VEGF in endothelial cells via NRF2-dependent mechanism: novel point of convergence between electrophilic and unfolded protein stress pathways.
Afonyushkin T, Oskolkova OV, Philippova M, Resink TJ, Erne P, Binder BR, Bochkov VN. Afonyushkin T, et al. Among authors: bochkov vn. Arterioscler Thromb Vasc Biol. 2010 May;30(5):1007-13. doi: 10.1161/ATVBAHA.110.204354. Epub 2010 Feb 25. Arterioscler Thromb Vasc Biol. 2010. PMID: 20185790
139 results