Furr J - Search Results

1

Dipentyl phthalate dosing during sexual differentiation disrupts fetal testis function and postnatal development of the male Sprague-Dawley rat with greater relative potency than other phthalates.

Hannas BR, Furr J, Lambright CS, Wilson VS, Foster PM, Gray LE Jr. Hannas BR, et al. Among authors: furr j. Toxicol Sci. 2011 Mar;120(1):184-93. doi: 10.1093/toxsci/kfq386. Epub 2010 Dec 20. Toxicol Sci. 2011. PMID: 21177253 Free PMC article.

2

The herbicide linuron reduces testosterone production from the fetal rat testis during both in utero and in vitro exposures.

Wilson VS, Lambright CR, Furr JR, Howdeshell KL, Earl Gray L Jr. Wilson VS, et al. Toxicol Lett. 2009 Apr 25;186(2):73-7. doi: 10.1016/j.toxlet.2008.12.017. Epub 2009 Jan 9. Toxicol Lett. 2009. PMID: 19167474

3

Transgenerational effects of Di (2-ethylhexyl) phthalate in the male CRL:CD(SD) rat: added value of assessing multiple offspring per litter.

Gray LE Jr, Barlow NJ, Howdeshell KL, Ostby JS, Furr JR, Gray CL. Gray LE Jr, et al. Among authors: furr jr. Toxicol Sci. 2009 Aug;110(2):411-25. doi: 10.1093/toxsci/kfp109. Epub 2009 May 29. Toxicol Sci. 2009. PMID: 19482887 Free PMC article.

4

A short-term in vivo screen using fetal testosterone production, a key event in the phthalate adverse outcome pathway, to predict disruption of sexual differentiation.

Furr JR, Lambright CS, Wilson VS, Foster PM, Gray LE Jr. Furr JR, et al. Toxicol Sci. 2014 Aug 1;140(2):403-24. doi: 10.1093/toxsci/kfu081. Epub 2014 May 5. Toxicol Sci. 2014. PMID: 24798384 Free PMC article.

5

Simvastatin and dipentyl phthalate lower ex vivo testicular testosterone production and exhibit additive effects on testicular testosterone and gene expression via distinct mechanistic pathways in the fetal rat.

Beverly BE, Lambright CS, Furr JR, Sampson H, Wilson VS, McIntyre BS, Foster PM, Travlos G, Gray LE Jr. Beverly BE, et al. Among authors: furr jr. Toxicol Sci. 2014 Oct;141(2):524-37. doi: 10.1093/toxsci/kfu149. Epub 2014 Jul 23. Toxicol Sci. 2014. PMID: 25055962 Free PMC article.

6

Dose Addition Models Based on Biologically Relevant Reductions in Fetal Testosterone Accurately Predict Postnatal Reproductive Tract Alterations by a Phthalate Mixture in Rats.

Howdeshell KL, Rider CV, Wilson VS, Furr JR, Lambright CR, Gray LE Jr. Howdeshell KL, et al. Toxicol Sci. 2015 Dec;148(2):488-502. doi: 10.1093/toxsci/kfv196. Epub 2015 Sep 8. Toxicol Sci. 2015. PMID: 26350170 Free PMC article.

7

A Demonstration of the Uncertainty in Predicting the Estrogenic Activity of Individual Chemicals and Mixtures From an In Vitro Estrogen Receptor Transcriptional Activation Assay (T47D-KBluc) to the In Vivo Uterotrophic Assay Using Oral Exposure.

Conley JM, Hannas BR, Furr JR, Wilson VS, Gray LE Jr. Conley JM, et al. Toxicol Sci. 2016 Oct;153(2):382-95. doi: 10.1093/toxsci/kfw134. Epub 2016 Jul 29. Toxicol Sci. 2016. PMID: 27473340 Free PMC article.

8

In utero exposure to simvastatin reduces postnatal survival and permanently alters reproductive tract development in the Crl:CD(SD) male rat.

Beverly BEJ, Furr JR, Lambright CS, Wilson VS, McIntyre BS, Foster PMD, Travlos G, Earl Gray L Jr. Beverly BEJ, et al. Among authors: furr jr. Toxicol Appl Pharmacol. 2019 Feb 15;365:112-123. doi: 10.1016/j.taap.2019.01.001. Epub 2019 Jan 11. Toxicol Appl Pharmacol. 2019. PMID: 30639414 Free PMC article.

9

A Conflicted Tale of Two Novel AR Antagonists In Vitro and In Vivo: Pyrifluquinazon Versus Bisphenol C.

Gray LE, Furr JR, Conley JM, Lambright CS, Evans N, Cardon MC, Wilson VS, Foster PM, Hartig PC. Gray LE, et al. Toxicol Sci. 2019 Apr 1;168(2):632-643. doi: 10.1093/toxsci/kfz010. Toxicol Sci. 2019. PMID: 30649549 Free PMC article.

10

Quantification of the Uncertainties in Extrapolating From In Vitro Androgen Receptor Antagonism to In Vivo Hershberger Assay Endpoints and Adverse Reproductive Development in Male Rats.

Gray LE, Furr JR, Lambright CS, Evans N, Hartig PC, Cardon MC, Wilson VS, Hotchkiss AK, Conley JM. Gray LE, et al. Toxicol Sci. 2020 Aug 1;176(2):297-311. doi: 10.1093/toxsci/kfaa067. Toxicol Sci. 2020. PMID: 32421828 Free PMC article.

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