He R - Search Results

1

MicroRNA-regulated, systemically delivered rAAV9: a step closer to CNS-restricted transgene expression.

Xie J, Xie Q, Zhang H, Ameres SL, Hung JH, Su Q, He R, Mu X, Seher Ahmed S, Park S, Kato H, Li C, Mueller C, Mello CC, Weng Z, Flotte TR, Zamore PD, Gao G. Xie J, et al. Among authors: he r. Mol Ther. 2011 Mar;19(3):526-35. doi: 10.1038/mt.2010.279. Epub 2010 Dec 21. Mol Ther. 2011. PMID: 21179009 Free PMC article.

2

Several rAAV vectors efficiently cross the blood-brain barrier and transduce neurons and astrocytes in the neonatal mouse central nervous system.

Zhang H, Yang B, Mu X, Ahmed SS, Su Q, He R, Wang H, Mueller C, Sena-Esteves M, Brown R, Xu Z, Gao G. Zhang H, et al. Among authors: he r. Mol Ther. 2011 Aug;19(8):1440-8. doi: 10.1038/mt.2011.98. Epub 2011 May 24. Mol Ther. 2011. PMID: 21610699 Free PMC article.

3

Long-term, efficient inhibition of microRNA function in mice using rAAV vectors.

Xie J, Ameres SL, Friedline R, Hung JH, Zhang Y, Xie Q, Zhong L, Su Q, He R, Li M, Li H, Mu X, Zhang H, Broderick JA, Kim JK, Weng Z, Flotte TR, Zamore PD, Gao G. Xie J, et al. Among authors: he r. Nat Methods. 2012 Mar 4;9(4):403-9. doi: 10.1038/nmeth.1903. Nat Methods. 2012. PMID: 22388288 Free PMC article.

4

Global CNS transduction of adult mice by intravenously delivered rAAVrh.8 and rAAVrh.10 and nonhuman primates by rAAVrh.10.

Yang B, Li S, Wang H, Guo Y, Gessler DJ, Cao C, Su Q, Kramer J, Zhong L, Ahmed SS, Zhang H, He R, Desrosiers RC, Brown R, Xu Z, Gao G. Yang B, et al. Among authors: he r. Mol Ther. 2014 Jul;22(7):1299-1309. doi: 10.1038/mt.2014.68. Epub 2014 Apr 30. Mol Ther. 2014. PMID: 24781136 Free PMC article.

5

Empty Virions In AAV8 Vector Preparations Reduce Transduction Efficiency And May Cause Total Viral Particle Dose-Limiting Side-Effects.

Gao K, Li M, Zhong L, Su Q, Li J, Li S, He R, Zhang Y, Hendricks G, Wang J, Gao G. Gao K, et al. Among authors: he r. Mol Ther Methods Clin Dev. 2014;1(9):20139. doi: 10.1038/mtm.2013.9. Mol Ther Methods Clin Dev. 2014. PMID: 25485285 Free PMC article.

6

Efficient and Targeted Transduction of Nonhuman Primate Liver With Systemically Delivered Optimized AAV3B Vectors.

Li S, Ling C, Zhong L, Li M, Su Q, He R, Tang Q, Greiner DL, Shultz LD, Brehm MA, Flotte TR, Mueller C, Srivastava A, Gao G. Li S, et al. Among authors: he r. Mol Ther. 2015 Dec;23(12):1867-76. doi: 10.1038/mt.2015.174. Epub 2015 Sep 25. Mol Ther. 2015. PMID: 26403887 Free PMC article.

7

Short DNA Hairpins Compromise Recombinant Adeno-Associated Virus Genome Homogeneity.

Xie J, Mao Q, Tai PWL, He R, Ai J, Su Q, Zhu Y, Ma H, Li J, Gong S, Wang D, Gao Z, Li M, Zhong L, Zhou H, Gao G. Xie J, et al. Among authors: he r. Mol Ther. 2017 Jun 7;25(6):1363-1374. doi: 10.1016/j.ymthe.2017.03.028. Epub 2017 Apr 24. Mol Ther. 2017. PMID: 28462820 Free PMC article.

8

A Rationally Engineered Capsid Variant of AAV9 for Systemic CNS-Directed and Peripheral Tissue-Detargeted Gene Delivery in Neonates.

Wang D, Li S, Gessler DJ, Xie J, Zhong L, Li J, Tran K, Van Vliet K, Ren L, Su Q, He R, Goetzmann JE, Flotte TR, Agbandje-McKenna M, Gao G. Wang D, et al. Among authors: he r. Mol Ther Methods Clin Dev. 2018 Mar 16;9:234-246. doi: 10.1016/j.omtm.2018.03.004. eCollection 2018 Jun 15. Mol Ther Methods Clin Dev. 2018. PMID: 29766031 Free PMC article.

9

Adeno-Associated Virus Neutralizing Antibodies in Large Animals and Their Impact on Brain Intraparenchymal Gene Transfer.

Wang D, Zhong L, Li M, Li J, Tran K, Ren L, He R, Xie J, Moser RP, Fraser C, Kuchel T, Sena-Esteves M, Flotte TR, Aronin N, Gao G. Wang D, et al. Among authors: he r. Mol Ther Methods Clin Dev. 2018 Oct 4;11:65-72. doi: 10.1016/j.omtm.2018.09.003. eCollection 2018 Dec 14. Mol Ther Methods Clin Dev. 2018. PMID: 30397628 Free PMC article.

10

High-Throughput Quantification of In Vivo Adeno-Associated Virus Transduction with Barcoded Non-Coding RNAs.

Xu M, Li J, Xie J, He R, Su Q, Gao G, Tai PWL. Xu M, et al. Among authors: he r. Hum Gene Ther. 2019 Aug;30(8):946-956. doi: 10.1089/hum.2018.253. Epub 2019 Jun 17. Hum Gene Ther. 2019. PMID: 31072208 Free PMC article.

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