Mueller C - Search Results

1

MicroRNA-regulated, systemically delivered rAAV9: a step closer to CNS-restricted transgene expression.

Xie J, Xie Q, Zhang H, Ameres SL, Hung JH, Su Q, He R, Mu X, Seher Ahmed S, Park S, Kato H, Li C, Mueller C, Mello CC, Weng Z, Flotte TR, Zamore PD, Gao G. Xie J, et al. Among authors: mueller c. Mol Ther. 2011 Mar;19(3):526-35. doi: 10.1038/mt.2010.279. Epub 2010 Dec 21. Mol Ther. 2011. PMID: 21179009 Free PMC article.

2

In vivo post-transcriptional gene silencing of alpha-1 antitrypsin by adeno-associated virus vectors expressing siRNA.

Cruz PE, Mueller C, Cossette TL, Golant A, Tang Q, Beattie SG, Brantly M, Campbell-Thompson M, Blomenkamp KS, Teckman JH, Flotte TR. Cruz PE, et al. Among authors: mueller c. Lab Invest. 2007 Sep;87(9):893-902. doi: 10.1038/labinvest.3700629. Epub 2007 Jun 25. Lab Invest. 2007. PMID: 17592477 Free article.

3

The promise of gene therapy for the treatment of alpha-1 antitrypsin deficiency.

Cruz PE, Mueller C, Flotte TR. Cruz PE, et al. Among authors: mueller c. Pharmacogenomics. 2007 Sep;8(9):1191-8. doi: 10.2217/14622416.8.9.1191. Pharmacogenomics. 2007. PMID: 17924834 Review.

4

Partial correction of the CFTR-dependent ABPA mouse model with recombinant adeno-associated virus gene transfer of truncated CFTR gene.

Mueller C, Torrez D, Braag S, Martino A, Clarke T, Campbell-Thompson M, Flotte TR. Mueller C, et al. J Gene Med. 2008 Jan;10(1):51-60. doi: 10.1002/jgm.1119. J Gene Med. 2008. PMID: 18023072

5

Clinical gene therapy using recombinant adeno-associated virus vectors.

Mueller C, Flotte TR. Mueller C, et al. Gene Ther. 2008 Jun;15(11):858-63. doi: 10.1038/gt.2008.68. Epub 2008 Apr 17. Gene Ther. 2008. PMID: 18418415 Review.

6

Apparently nonspecific enzyme elevations after portal vein delivery of recombinant adeno-associated virus serotype 2 vector in hepatitis C virus-infected chimpanzees.

Flotte TR, Goetzmann J, Caridi J, Paolillo J, Conlon TJ, Potter M, Mueller C, Byrne BJ. Flotte TR, et al. Among authors: mueller c. Hum Gene Ther. 2008 Jul;19(7):681-9. doi: 10.1089/hum.2007.174. Hum Gene Ther. 2008. PMID: 18588426 Free PMC article.

7

Gene therapy for cystic fibrosis.

Mueller C, Flotte TR. Mueller C, et al. Clin Rev Allergy Immunol. 2008 Dec;35(3):164-78. doi: 10.1007/s12016-008-8080-3. Clin Rev Allergy Immunol. 2008. PMID: 18600482 Review.

8

The pros and cons of immunomodulatory IL-10 gene therapy with recombinant AAV in a Cftr-/- -dependent allergy mouse model.

Mueller C, Braag SA, Martino AT, Tang Q, Campbell-Thompson M, Flotte TR. Mueller C, et al. Gene Ther. 2009 Feb;16(2):172-83. doi: 10.1038/gt.2008.156. Epub 2008 Sep 25. Gene Ther. 2009. PMID: 18818669

9

Recombinant AAV serotype and capsid mutant comparison for pulmonary gene transfer of alpha-1-antitrypsin using invasive and noninvasive delivery.

Liqun Wang R, McLaughlin T, Cossette T, Tang Q, Foust K, Campbell-Thompson M, Martino A, Cruz P, Loiler S, Mueller C, Flotte TR. Liqun Wang R, et al. Among authors: mueller c. Mol Ther. 2009 Jan;17(1):81-7. doi: 10.1038/mt.2008.217. Epub 2008 Oct 21. Mol Ther. 2009. PMID: 18941444 Free PMC article.

10

Sustained transgene expression despite T lymphocyte responses in a clinical trial of rAAV1-AAT gene therapy.

Brantly ML, Chulay JD, Wang L, Mueller C, Humphries M, Spencer LT, Rouhani F, Conlon TJ, Calcedo R, Betts MR, Spencer C, Byrne BJ, Wilson JM, Flotte TR. Brantly ML, et al. Among authors: mueller c. Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16363-8. doi: 10.1073/pnas.0904514106. Epub 2009 Aug 12. Proc Natl Acad Sci U S A. 2009. PMID: 19706466 Free PMC article. Clinical Trial.

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