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Page 1
Polymorphisms in the multidrug resistance gene MDR1 (ABCB1) predict for molecular resistance in patients with newly diagnosed chronic myeloid leukemia receiving high-dose imatinib.
Deenik W, van der Holt B, Janssen JJ, Chu IW, Valk PJ, Ossenkoppele GJ, van der Heiden IP, Sonneveld P, van Schaik RH, Cornelissen JJ. Deenik W, et al. Among authors: chu iw. Blood. 2010 Dec 23;116(26):6144-5; author reply 6145-6. doi: 10.1182/blood-2010-07-296954. Blood. 2010. PMID: 21183698 Free article. No abstract available.
High-dose imatinib versus high-dose imatinib in combination with intermediate-dose cytarabine in patients with first chronic phase myeloid leukemia: a randomized phase III trial of the Dutch-Belgian HOVON study group.
Thielen N, van der Holt B, Verhoef GE, Ammerlaan RA, Sonneveld P, Janssen JJ, Deenik W, Falkenburg JH, Kersten MJ, Sinnige HA, Schipperus M, Schattenberg A, van Marwijk Kooy R, Smit WM, Chu IW, Valk PJ, Ossenkoppele GJ, Cornelissen JJ. Thielen N, et al. Among authors: chu iw. Ann Hematol. 2013 Aug;92(8):1049-56. doi: 10.1007/s00277-013-1730-4. Epub 2013 Apr 10. Ann Hematol. 2013. PMID: 23572137 Clinical Trial.
Addition of β-mercaptoethanol is a prerequisite for high-quality RNA isolation using QIAsymphony technology as demonstrated by detection of molecular aberrations in hematologic malignancies.
van der Poel-van de Luytgaarde SC, Geertsma-Kleinekoort WM, Goudswaard CS, Hogenbirk-Hupkes PE, van Hoven-Beijen MA, van de Werf M, Chu IW, van Kapel J, Valk PJ. van der Poel-van de Luytgaarde SC, et al. Among authors: chu iw. Genet Test Mol Biomarkers. 2013 Jun;17(6):475-80. doi: 10.1089/gtmb.2012.0448. Epub 2013 Apr 24. Genet Test Mol Biomarkers. 2013. PMID: 23614569
Integrated genome-wide genotyping and gene expression profiling reveals BCL11B as a putative oncogene in acute myeloid leukemia with 14q32 aberrations.
Abbas S, Sanders MA, Zeilemaker A, Geertsma-Kleinekoort WM, Koenders JE, Kavelaars FG, Abbas ZG, Mahamoud S, Chu IW, Hoogenboezem R, Peeters JK, van Drunen E, van Galen J, Beverloo HB, Löwenberg B, Valk PJ. Abbas S, et al. Among authors: chu iw. Haematologica. 2014 May;99(5):848-57. doi: 10.3324/haematol.2013.095604. Epub 2014 Jan 17. Haematologica. 2014. PMID: 24441149 Free PMC article.
Somatic calreticulin mutations in patients with Budd-Chiari syndrome and portal vein thrombosis.
Plompen EP, Valk PJ, Chu I, Darwish Murad SD, Plessier A, Turon F, Trebicka J, Primignani M, Garcia-Pagán JC, Valla DC, Janssen HL, Leebeek FW; European Network for Vascular Disorders of the Liver (EN-Vie). Plompen EP, et al. Haematologica. 2015 Jun;100(6):e226-8. doi: 10.3324/haematol.2014.120857. Epub 2015 Feb 14. Haematologica. 2015. PMID: 25682604 Free PMC article. No abstract available.
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