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Polymorphisms in the multidrug resistance gene MDR1 (ABCB1) predict for molecular resistance in patients with newly diagnosed chronic myeloid leukemia receiving high-dose imatinib.
Deenik W, van der Holt B, Janssen JJ, Chu IW, Valk PJ, Ossenkoppele GJ, van der Heiden IP, Sonneveld P, van Schaik RH, Cornelissen JJ. Deenik W, et al. Among authors: van der heiden ip. Blood. 2010 Dec 23;116(26):6144-5; author reply 6145-6. doi: 10.1182/blood-2010-07-296954. Blood. 2010. PMID: 21183698 Free article. No abstract available.
MDR1 gene polymorphisms are associated with neuropsychiatric adverse effects of mefloquine.
Aarnoudse AL, van Schaik RH, Dieleman J, Molokhia M, van Riemsdijk MM, Ligthelm RJ, Overbosch D, van der Heiden IP, Stricker BH. Aarnoudse AL, et al. Among authors: van schaik rh, van riemsdijk mm, van der heiden ip. Clin Pharmacol Ther. 2006 Oct;80(4):367-74. doi: 10.1016/j.clpt.2006.07.003. Clin Pharmacol Ther. 2006. PMID: 17015054
Maternal medication use, carriership of the ABCB1 3435C > T polymorphism and the risk of a child with cleft lip with or without cleft palate.
Bliek BJ, van Schaik RH, van der Heiden IP, Sayed-Tabatabaei FA, van Duijn CM, Steegers EA, Steegers-Theunissen RP; Eurocran Gene-Environment Interaction Group. Bliek BJ, et al. Among authors: van der heiden ip. Am J Med Genet A. 2009 Oct;149A(10):2088-92. doi: 10.1002/ajmg.a.33036. Am J Med Genet A. 2009. PMID: 19760622
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