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Page 1
Metformin: from mechanisms of action to therapies.
Foretz M, Guigas B, Bertrand L, Pollak M, Viollet B. Foretz M, et al. Among authors: viollet b. Cell Metab. 2014 Dec 2;20(6):953-66. doi: 10.1016/j.cmet.2014.09.018. Epub 2014 Oct 30. Cell Metab. 2014. PMID: 25456737 Free article. Review.
Metformin, independent of AMPK, inhibits mTORC1 in a rag GTPase-dependent manner.
Kalender A, Selvaraj A, Kim SY, Gulati P, Brûlé S, Viollet B, Kemp BE, Bardeesy N, Dennis P, Schlager JJ, Marette A, Kozma SC, Thomas G. Kalender A, et al. Among authors: viollet b. Cell Metab. 2010 May 5;11(5):390-401. doi: 10.1016/j.cmet.2010.03.014. Cell Metab. 2010. PMID: 20444419 Free PMC article.
AMPKα is essential for acute exercise-induced gene responses but not for exercise training-induced adaptations in mouse skeletal muscle.
Fentz J, Kjøbsted R, Kristensen CM, Hingst JR, Birk JB, Gudiksen A, Foretz M, Schjerling P, Viollet B, Pilegaard H, Wojtaszewski JF. Fentz J, et al. Among authors: viollet b. Am J Physiol Endocrinol Metab. 2015 Dec 1;309(11):E900-14. doi: 10.1152/ajpendo.00157.2015. Epub 2015 Sep 29. Am J Physiol Endocrinol Metab. 2015. PMID: 26419588 Free article.
Inducible deletion of skeletal muscle AMPKα reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during exercise.
Hingst JR, Kjøbsted R, Birk JB, Jørgensen NO, Larsen MR, Kido K, Larsen JK, Kjeldsen SAS, Fentz J, Frøsig C, Holm S, Fritzen AM, Dohlmann TL, Larsen S, Foretz M, Viollet B, Schjerling P, Overby P, Halling JF, Pilegaard H, Hellsten Y, Wojtaszewski JFP. Hingst JR, et al. Among authors: viollet b. Mol Metab. 2020 Oct;40:101028. doi: 10.1016/j.molmet.2020.101028. Epub 2020 Jun 3. Mol Metab. 2020. PMID: 32504885 Free PMC article.
Deletion of intestinal epithelial AMP-activated protein kinase alters distal colon permeability but not glucose homeostasis.
Olivier S, Pochard C, Diounou H, Castillo V, Divoux J, Alcantara J, Leclerc J, Guilmeau S, Huet C, Charifi W, Varin TV, Daniel N, Foretz M, Neunlist M, Salomon BL, Ghosh P, Marette A, Rolli-Derkinderen M, Viollet B. Olivier S, et al. Among authors: viollet b. Mol Metab. 2021 May;47:101183. doi: 10.1016/j.molmet.2021.101183. Epub 2021 Feb 4. Mol Metab. 2021. PMID: 33548500 Free PMC article.
359 results