Melchiorre C - Search Results

1

Multitargeted drugs discovery: balancing anti-amyloid and anticholinesterase capacity in a single chemical entity.

Bolognesi ML, Bartolini M, Tarozzi A, Morroni F, Lizzi F, Milelli A, Minarini A, Rosini M, Hrelia P, Andrisano V, Melchiorre C. Bolognesi ML, et al. Among authors: melchiorre c. Bioorg Med Chem Lett. 2011 May 1;21(9):2655-8. doi: 10.1016/j.bmcl.2010.12.093. Epub 2010 Dec 23. Bioorg Med Chem Lett. 2011. PMID: 21236667

2

Structure-activity relationships of methoctramine-related polyamines as muscular nicotinic receptor noncompetitive antagonists. 3. Effect of inserting the tetraamine backbone into a macrocyclic structure.

Bolognesi ML, Bixel MG, Marucci G, Bartolini M, Krauss M, Angeli P, Antonello A, Rosini M, Tumiatti V, Hucho F, Melchiorre C. Bolognesi ML, et al. Among authors: melchiorre c. J Med Chem. 2002 Jul 18;45(15):3286-95. doi: 10.1021/jm020835f. J Med Chem. 2002. PMID: 12109912

3

Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 2. Role of the substituents on the phenyl ring and nitrogen atoms of caproctamine.

Tumiatti V, Rosini M, Bartolini M, Cavalli A, Marucci G, Andrisano V, Angeli P, Banzi R, Minarini A, Recanatini M, Melchiorre C. Tumiatti V, et al. Among authors: melchiorre c. J Med Chem. 2003 Mar 13;46(6):954-66. doi: 10.1021/jm021055+. J Med Chem. 2003. PMID: 12620072

4

Rosini M, Antonello A, Cavalli A, Bolognesi ML, Minarini A, Marucci G, Poggesi E, Leonardi A, Melchiorre C. Rosini M, et al. Among authors: melchiorre c. J Med Chem. 2003 Nov 6;46(23):4895-903. doi: 10.1021/jm030952q. J Med Chem. 2003. PMID: 14584940

5

Design, synthesis, and biological evaluation of conformationally restricted rivastigmine analogues.

Bolognesi ML, Bartolini M, Cavalli A, Andrisano V, Rosini M, Minarini A, Melchiorre C. Bolognesi ML, et al. Among authors: melchiorre c. J Med Chem. 2004 Nov 18;47(24):5945-52. doi: 10.1021/jm049782n. J Med Chem. 2004. PMID: 15537349

6

Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 3. Effect of replacing the inner polymethylene chain with cyclic moieties.

Tumiatti V, Andrisano V, Banzi R, Bartolini M, Minarini A, Rosini M, Melchiorre C. Tumiatti V, et al. Among authors: melchiorre c. J Med Chem. 2004 Dec 16;47(26):6490-8. doi: 10.1021/jm0494366. J Med Chem. 2004. PMID: 15588084

7

Propidium-based polyamine ligands as potent inhibitors of acetylcholinesterase and acetylcholinesterase-induced amyloid-beta aggregation.

Bolognesi ML, Andrisano V, Bartolini M, Banzi R, Melchiorre C. Bolognesi ML, et al. Among authors: melchiorre c. J Med Chem. 2005 Jan 13;48(1):24-7. doi: 10.1021/jm049156q. J Med Chem. 2005. PMID: 15633997

8

Design, synthesis, and biological evaluation of prazosin-related derivatives as multipotent compounds.

Antonello A, Hrelia P, Leonardi A, Marucci G, Rosini M, Tarozzi A, Tumiatti V, Melchiorre C. Antonello A, et al. Among authors: melchiorre c. J Med Chem. 2005 Jan 13;48(1):28-31. doi: 10.1021/jm049153d. J Med Chem. 2005. PMID: 15633998

9

Rational approach to discover multipotent anti-Alzheimer drugs.

Rosini M, Andrisano V, Bartolini M, Bolognesi ML, Hrelia P, Minarini A, Tarozzi A, Melchiorre C. Rosini M, et al. Among authors: melchiorre c. J Med Chem. 2005 Jan 27;48(2):360-3. doi: 10.1021/jm049112h. J Med Chem. 2005. PMID: 15658850

10

Design, synthesis, and biological evaluation of substituted 2,3-dihydro-1H-cyclopenta[b]quinolin-9-ylamine related compounds as fructose-1,6-bisphosphatase inhibitors.

Rosini M, Mancini F, Tarozzi A, Colizzi F, Andrisano V, Bolognesi ML, Hrelia P, Melchiorre C. Rosini M, et al. Among authors: melchiorre c. Bioorg Med Chem. 2006 Dec 1;14(23):7846-53. doi: 10.1016/j.bmc.2006.07.059. Bioorg Med Chem. 2006. PMID: 16908175

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