Elevated amyloid beta protein (Abeta42) and late onset Alzheimer's disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene.
Ertekin-Taner N, Ronald J, Feuk L, Prince J, Tucker M, Younkin L, Hella M, Jain S, Hackett A, Scanlin L, Kelly J, Kihiko-Ehman M, Neltner M, Hersh L, Kindy M, Markesbery W, Hutton M, de Andrade M, Petersen RC, Graff-Radford N, Estus S, Brookes AJ, Younkin SG.
Ertekin-Taner N, et al.
Hum Mol Genet. 2005 Feb 1;14(3):447-60. doi: 10.1093/hmg/ddi041. Epub 2004 Dec 22.
Hum Mol Genet. 2005.
PMID: 15615772