Nagase H - Search Results

1

Synthesis of 6,14-epoxymorphinan derivatives and their pharmacologies.

Nemoto T, Yamamoto N, Watanabe A, Fujii H, Hasebe K, Nakajima M, Mochizuki H, Nagase H. Nemoto T, et al. Among authors: nagase h. Bioorg Med Chem. 2011 Feb 1;19(3):1205-21. doi: 10.1016/j.bmc.2010.12.035. Epub 2010 Dec 21. Bioorg Med Chem. 2011. PMID: 21256034

2

Role of spacer and address components in peptidomimetic delta opioid receptor antagonists related to naltrindole.

Portoghese PS, Nagase H, MaloneyHuss KE, Lin CE, Takemori AE. Portoghese PS, et al. Among authors: nagase h. J Med Chem. 1991 May;34(5):1715-20. doi: 10.1021/jm00109a027. J Med Chem. 1991. PMID: 1851846

3

Discovery of a structurally novel opioid kappa-agonist derived from 4,5-epoxymorphinan.

Nagase H, Hayakawa J, Kawamura K, Kawai K, Takezawa Y, Matsuura H, Tajima C, Endo T. Nagase H, et al. Chem Pharm Bull (Tokyo). 1998 Feb;46(2):366-9. doi: 10.1248/cpb.46.366. Chem Pharm Bull (Tokyo). 1998. PMID: 9501472

4

The pharmacological profile of delta opioid receptor ligands, (+) and (-) TAN-67 on pain modulation.

Nagase H, Yajima Y, Fujii H, Kawamura K, Narita M, Kamei J, Suzuki T. Nagase H, et al. Life Sci. 2001 Apr 6;68(19-20):2227-31. doi: 10.1016/s0024-3205(01)01010-4. Life Sci. 2001. PMID: 11358331 Review.

5

Synthesis of optically active TAN-67, a highly selective delta opioid receptor agonist, and investigation of its pharmacological properties.

Fujii H, Kawai K, Kawamura K, Mizusuna A, Onoda Y, Murachi M, Tanaka T, Endoh T, Nagase H. Fujii H, et al. Among authors: nagase h. Drug Des Discov. 2001;17(4):325-30. Drug Des Discov. 2001. PMID: 11765135

6

The first example of the stereoselective synthesis of 7 beta-carbamoyl-4,5alpha-epoxymorphinan via a novel and reactive gamma-lactone.

Fujii H, Hirano N, Uchiro H, Kawamura K, Nagase H. Fujii H, et al. Among authors: nagase h. Chem Pharm Bull (Tokyo). 2004 Jun;52(6):747-50. doi: 10.1248/cpb.52.747. Chem Pharm Bull (Tokyo). 2004. PMID: 15187399 Free article.

7

Drug design and synthesis of epsilon opioid receptor agonist: 17-(cyclopropylmethyl)-4,5alpha-epoxy-3,6beta-dihydroxy-6,14-endoethenomorphinan-7alpha-(N-methyl-N-phenethyl)carboxamide (TAN-821) inducing antinociception mediated by putative epsilon opioid receptor.

Fujii H, Narita M, Mizoguchi H, Murachi M, Tanaka T, Kawai K, Tseng LF, Nagase H. Fujii H, et al. Among authors: nagase h. Bioorg Med Chem. 2004 Aug 1;12(15):4133-45. doi: 10.1016/j.bmc.2004.05.024. Bioorg Med Chem. 2004. PMID: 15246090

8

Rational drug design and synthesis of a selective opioid receptor antagonist on the basis of the accessory site concept.

Fujii H, Narita M, Mizoguchi H, Hirokawa J, Kawai K, Tanaka T, Tseng LF, Nagase H. Fujii H, et al. Among authors: nagase h. Bioorg Med Chem Lett. 2004 Aug 16;14(16):4241-3. doi: 10.1016/j.bmcl.2004.06.004. Bioorg Med Chem Lett. 2004. PMID: 15261278

9

Implications of protein kinase C in the nucleus accumbens in the development of sensitization to methamphetamine in rats.

Narita M, Akai H, Nagumo Y, Sunagawa N, Hasebe K, Nagase H, Kita T, Hara C, Suzuki T. Narita M, et al. Among authors: nagase h. Neuroscience. 2004;127(4):941-8. doi: 10.1016/j.neuroscience.2004.06.017. Neuroscience. 2004. PMID: 15312906

10

Possible pharmacotherapy of the opioid kappa receptor agonist for drug dependence.

Hasebe K, Kawai K, Suzuki T, Kawamura K, Tanaka T, Narita M, Nagase H, Suzuki T. Hasebe K, et al. Among authors: nagase h. Ann N Y Acad Sci. 2004 Oct;1025:404-13. doi: 10.1196/annals.1316.050. Ann N Y Acad Sci. 2004. PMID: 15542743 Review.

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