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Correlation of nitrosourea murine bone marrow toxicity with deoxyribonucleic acid alkylation and chromatin binding sites.
Green D, Tew KD, Hisamatsu T, Schein PS. Green D, et al. Biochem Pharmacol. 1982 May 1;31(9):1671-9. doi: 10.1016/0006-2952(82)90667-0. Biochem Pharmacol. 1982. PMID: 7104031
A reduction in this toxicity can be achieved by attaching the chloroethylnitrosourea cytotoxic group to C2 (chlorozotocin) or C1 (1-(2-chloroethyl)-3-(beta-D-glucopyranosyl)-1-nitrosourea, GANU) of glucose. Both glucose analogs are less myelotoxic in mice than 1-(2-chloroe …
A reduction in this toxicity can be achieved by attaching the chloroethylnitrosourea cytotoxic group to C2 (chlorozotocin) or C1 (1-(2-chlor …
Pharmacology of nitrosourea antitumor agents.
Schein PS, Heal J, Green D, Woolley PV. Schein PS, et al. Among authors: green d. Antibiot Chemother (1971). 1978;23:64-75. doi: 10.1159/000401473. Antibiot Chemother (1971). 1978. PMID: 148237 No abstract available.
6,188 results