Towne JE - Search Results

1

Anti-IL-23 monoclonal antibody synergizes in combination with targeted therapies or IL-2 to suppress tumor growth and metastases.

Teng MW, von Scheidt B, Duret H, Towne JE, Smyth MJ. Teng MW, et al. Among authors: towne je. Cancer Res. 2011 Mar 15;71(6):2077-86. doi: 10.1158/0008-5472.CAN-10-3994. Epub 2011 Jan 31. Cancer Res. 2011. PMID: 21282337

2

Opposing roles for IL-23 and IL-12 in maintaining occult cancer in an equilibrium state.

Teng MW, Vesely MD, Duret H, McLaughlin N, Towne JE, Schreiber RD, Smyth MJ. Teng MW, et al. Among authors: towne je. Cancer Res. 2012 Aug 15;72(16):3987-96. doi: 10.1158/0008-5472.CAN-12-1337. Epub 2012 Aug 6. Cancer Res. 2012. PMID: 22869585 Free PMC article.

3

Combined anti-CD40 and anti-IL-23 monoclonal antibody therapy effectively suppresses tumor growth and metastases.

von Scheidt B, Leung PS, Yong MC, Zhang Y, Towne JE, Smyth MJ, Teng MW. von Scheidt B, et al. Among authors: towne je. Cancer Res. 2014 May 1;74(9):2412-21. doi: 10.1158/0008-5472.CAN-13-1646. Epub 2014 Feb 20. Cancer Res. 2014. PMID: 24556719

4

Preclinical development of AMG 139, a human antibody specifically targeting IL-23.

Köck K, Pan WJ, Gow JM, Horner MJ, Gibbs JP, Colbert A, Goletz TJ, Newhall KJ, Rees WA, Sun Y, Zhang Y, O'Neill JC, Umble-Romero AN, Prokop SP, Krill CD, Som L, Buntich SA, Trimble MW, Tsuji WH, Towne JE. Köck K, et al. Among authors: towne je. Br J Pharmacol. 2015 Jan;172(1):159-72. doi: 10.1111/bph.12904. Epub 2014 Dec 15. Br J Pharmacol. 2015. PMID: 25205227 Free PMC article.

5

Differential Roles for Interleukin-23 and Interleukin-17 in Intestinal Immunoregulation.

Maxwell JR, Zhang Y, Brown WA, Smith CL, Byrne FR, Fiorino M, Stevens E, Bigler J, Davis JA, Rottman JB, Budelsky AL, Symons A, Towne JE. Maxwell JR, et al. Among authors: towne je. Immunity. 2015 Oct 20;43(4):739-50. doi: 10.1016/j.immuni.2015.08.019. Epub 2015 Sep 29. Immunity. 2015. PMID: 26431947 Free article.

6

The severity of experimental arthritis is independent of IL-36 receptor signaling.

Lamacchia C, Palmer G, Rodriguez E, Martin P, Vigne S, Seemayer CA, Talabot-Ayer D, Towne JE, Gabay C. Lamacchia C, et al. Among authors: towne je. Arthritis Res Ther. 2013 Mar 1;15(2):R38. doi: 10.1186/ar4192. Arthritis Res Ther. 2013. PMID: 23452551 Free PMC article.

7

Are Th17 cells in the gut pathogenic or protective?

Symons A, Budelsky AL, Towne JE. Symons A, et al. Among authors: towne je. Mucosal Immunol. 2012 Jan;5(1):4-6. doi: 10.1038/mi.2011.51. Epub 2011 Nov 9. Mucosal Immunol. 2012. PMID: 22071661 Free article.

8

Blockade of IL-36 receptor signaling does not prevent from TNF-induced arthritis.

Derer A, Groetsch B, Harre U, Böhm C, Towne J, Schett G, Frey S, Hueber AJ. Derer A, et al. PLoS One. 2014 Aug 11;9(8):e101954. doi: 10.1371/journal.pone.0101954. eCollection 2014. PLoS One. 2014. PMID: 25111378 Free PMC article.

9

Effect of IL-17 receptor A blockade with brodalumab in inflammatory diseases.

Nirula A, Nilsen J, Klekotka P, Kricorian G, Erondu N, Towne JE, Russell CB, Martin DA, Budelsky AL. Nirula A, et al. Among authors: towne je. Rheumatology (Oxford). 2016 Dec;55(suppl 2):ii43-ii55. doi: 10.1093/rheumatology/kew346. Rheumatology (Oxford). 2016. PMID: 27856660 Review.

10

IL-36 in psoriasis.

Towne JE, Sims JE. Towne JE, et al. Curr Opin Pharmacol. 2012 Aug;12(4):486-90. doi: 10.1016/j.coph.2012.02.009. Epub 2012 Mar 5. Curr Opin Pharmacol. 2012. PMID: 22398321 Review.

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