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Potential of aspirin to inhibit thrombotic microangiopathy in alpha1,3-galactosyltransferase gene-knockout pig hearts after transplantation in baboons.
Dor FJ, Kuwaki K, Tseng YL, Shimizu A, Houser SL, Yamada K, Hawley RJ, Patience C, Awwad M, Fishman JA, Robson SC, Sachs DH, Schuurman HJ, Cooper DK. Dor FJ, et al. Among authors: hawley rj. Transplant Proc. 2005 Jan-Feb;37(1):489-90. doi: 10.1016/j.transproceed.2004.12.235. Transplant Proc. 2005. PMID: 15808685
Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue.
Yamada K, Yazawa K, Shimizu A, Iwanaga T, Hisashi Y, Nuhn M, O'Malley P, Nobori S, Vagefi PA, Patience C, Fishman J, Cooper DK, Hawley RJ, Greenstein J, Schuurman HJ, Awwad M, Sykes M, Sachs DH. Yamada K, et al. Among authors: hawley rj. Nat Med. 2005 Jan;11(1):32-4. doi: 10.1038/nm1172. Epub 2004 Dec 26. Nat Med. 2005. PMID: 15619627
Heart transplantation in baboons using alpha1,3-galactosyltransferase gene-knockout pigs as donors: initial experience.
Kuwaki K, Tseng YL, Dor FJ, Shimizu A, Houser SL, Sanderson TM, Lancos CJ, Prabharasuth DD, Cheng J, Moran K, Hisashi Y, Mueller N, Yamada K, Greenstein JL, Hawley RJ, Patience C, Awwad M, Fishman JA, Robson SC, Schuurman HJ, Sachs DH, Cooper DK. Kuwaki K, et al. Among authors: hawley rj. Nat Med. 2005 Jan;11(1):29-31. doi: 10.1038/nm1171. Epub 2004 Dec 26. Nat Med. 2005. PMID: 15619628
GalT-KO pig lungs are highly susceptible to acute vascular rejection in baboons, which may be mitigated by transgenic expression of hCD47 on porcine blood vessels.
Watanabe H, Sahara H, Nomura S, Tanabe T, Ekanayake-Alper DK, Boyd LK, Louras NJ, Asfour A, Danton MA, Ho SH, Arn SJ, Hawley RJ, Shimizu A, Nagayasu T, Ayares D, Lorber MI, Sykes M, Sachs DH, Yamada K. Watanabe H, et al. Among authors: hawley rj. Xenotransplantation. 2018 Sep;25(5):e12391. doi: 10.1111/xen.12391. Epub 2018 Mar 12. Xenotransplantation. 2018. PMID: 29527745 Free PMC article.
104 results