Doudna JA - Search Results

1

Optimized high-throughput screen for hepatitis C virus translation inhibitors.

Berry KE, Peng B, Koditek D, Beeman D, Pagratis N, Perry JK, Parrish J, Zhong W, Doudna JA, Shih IH. Berry KE, et al. Among authors: doudna ja. J Biomol Screen. 2011 Feb;16(2):211-20. doi: 10.1177/1087057110391665. J Biomol Screen. 2011. PMID: 21297107 Free PMC article.

2

Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA.

Ji H, Fraser CS, Yu Y, Leary J, Doudna JA. Ji H, et al. Among authors: doudna ja. Proc Natl Acad Sci U S A. 2004 Dec 7;101(49):16990-5. doi: 10.1073/pnas.0407402101. Epub 2004 Nov 24. Proc Natl Acad Sci U S A. 2004. PMID: 15563596 Free PMC article.

3

Structural roles for human translation factor eIF3 in initiation of protein synthesis.

Siridechadilok B, Fraser CS, Hall RJ, Doudna JA, Nogales E. Siridechadilok B, et al. Among authors: doudna ja. Science. 2005 Dec 2;310(5753):1513-5. doi: 10.1126/science.1118977. Science. 2005. PMID: 16322461

4

Structural and mechanistic insights into hepatitis C viral translation initiation.

Fraser CS, Doudna JA. Fraser CS, et al. Among authors: doudna ja. Nat Rev Microbiol. 2007 Jan;5(1):29-38. doi: 10.1038/nrmicro1558. Epub 2006 Nov 27. Nat Rev Microbiol. 2007. PMID: 17128284 Review.

5

eIF3j is located in the decoding center of the human 40S ribosomal subunit.

Fraser CS, Berry KE, Hershey JW, Doudna JA. Fraser CS, et al. Among authors: doudna ja. Mol Cell. 2007 Jun 22;26(6):811-9. doi: 10.1016/j.molcel.2007.05.019. Mol Cell. 2007. PMID: 17588516 Free article.

6

The pathway of hepatitis C virus mRNA recruitment to the human ribosome.

Fraser CS, Hershey JW, Doudna JA. Fraser CS, et al. Among authors: doudna ja. Nat Struct Mol Biol. 2009 Apr;16(4):397-404. doi: 10.1038/nsmb.1572. Epub 2009 Mar 15. Nat Struct Mol Biol. 2009. PMID: 19287397 Free PMC article.

7

The HCV IRES pseudoknot positions the initiation codon on the 40S ribosomal subunit.

Berry KE, Waghray S, Doudna JA. Berry KE, et al. Among authors: doudna ja. RNA. 2010 Aug;16(8):1559-69. doi: 10.1261/rna.2197210. Epub 2010 Jun 28. RNA. 2010. PMID: 20584896 Free PMC article.

8

Crystal structure of the HCV IRES central domain reveals strategy for start-codon positioning.

Berry KE, Waghray S, Mortimer SA, Bai Y, Doudna JA. Berry KE, et al. Among authors: doudna ja. Structure. 2011 Oct 12;19(10):1456-66. doi: 10.1016/j.str.2011.08.002. Structure. 2011. PMID: 22000514 Free PMC article.

9

Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3).

Sun C, Todorovic A, Querol-Audí J, Bai Y, Villa N, Snyder M, Ashchyan J, Lewis CS, Hartland A, Gradia S, Fraser CS, Doudna JA, Nogales E, Cate JH. Sun C, et al. Among authors: doudna ja. Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20473-8. doi: 10.1073/pnas.1116821108. Epub 2011 Dec 1. Proc Natl Acad Sci U S A. 2011. PMID: 22135459 Free PMC article.

10

Hepatitis C virus 3'UTR regulates viral translation through direct interactions with the host translation machinery.

Bai Y, Zhou K, Doudna JA. Bai Y, et al. Among authors: doudna ja. Nucleic Acids Res. 2013 Sep;41(16):7861-74. doi: 10.1093/nar/gkt543. Epub 2013 Jun 19. Nucleic Acids Res. 2013. PMID: 23783572 Free PMC article.

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