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362 results

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The expression of the ubiquitin ligase SIAH2 (seven in absentia homolog 2) is mediated through gene copy number in breast cancer and is associated with a basal-like phenotype and p53 expression.
Chan P, Möller A, Liu MC, Sceneay JE, Wong CS, Waddell N, Huang KT, Dobrovic A, Millar EK, O'Toole SA, McNeil CM, Sutherland RL, Bowtell DD, Fox SB. Chan P, et al. Among authors: bowtell dd. Breast Cancer Res. 2011 Feb 9;13(1):R19. doi: 10.1186/bcr2828. Breast Cancer Res. 2011. PMID: 21306611 Free PMC article.
An expression-based site of origin diagnostic method designed for clinical application to cancer of unknown origin.
Tothill RW, Kowalczyk A, Rischin D, Bousioutas A, Haviv I, van Laar RK, Waring PM, Zalcberg J, Ward R, Biankin AV, Sutherland RL, Henshall SM, Fong K, Pollack JR, Bowtell DD, Holloway AJ. Tothill RW, et al. Among authors: bowtell dd. Cancer Res. 2005 May 15;65(10):4031-40. doi: 10.1158/0008-5472.CAN-04-3617. Cancer Res. 2005. PMID: 15899792
Elucidation of the substrate binding site of Siah ubiquitin ligase.
House CM, Hancock NC, Möller A, Cromer BA, Fedorov V, Bowtell DD, Parker MW, Polekhina G. House CM, et al. Among authors: bowtell dd. Structure. 2006 Apr;14(4):695-701. doi: 10.1016/j.str.2005.12.013. Structure. 2006. PMID: 16615911 Free article.
High resolution melting for mutation scanning of TP53 exons 5-8.
Krypuy M, Ahmed AA, Etemadmoghadam D, Hyland SJ; Australian Ovarian Cancer Study Group; DeFazio A, Fox SB, Brenton JD, Bowtell DD, Dobrovic A. Krypuy M, et al. Among authors: bowtell dd. BMC Cancer. 2007 Aug 31;7:168. doi: 10.1186/1471-2407-7-168. BMC Cancer. 2007. PMID: 17764544 Free PMC article.
Novel molecular subtypes of serous and endometrioid ovarian cancer linked to clinical outcome.
Tothill RW, Tinker AV, George J, Brown R, Fox SB, Lade S, Johnson DS, Trivett MK, Etemadmoghadam D, Locandro B, Traficante N, Fereday S, Hung JA, Chiew YE, Haviv I; Australian Ovarian Cancer Study Group; Gertig D, DeFazio A, Bowtell DD. Tothill RW, et al. Among authors: bowtell dd. Clin Cancer Res. 2008 Aug 15;14(16):5198-208. doi: 10.1158/1078-0432.CCR-08-0196. Clin Cancer Res. 2008. PMID: 18698038
Inhibition of Siah ubiquitin ligase function.
Möller A, House CM, Wong CS, Scanlon DB, Liu MC, Ronai Z, Bowtell DD. Möller A, et al. Among authors: bowtell dd. Oncogene. 2009 Jan 15;28(2):289-96. doi: 10.1038/onc.2008.382. Epub 2008 Oct 13. Oncogene. 2009. PMID: 18850011 Free PMC article.
362 results