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Page 1
SirT1 brings stemness closer to cancer and aging.
Calvanese V, Fraga MF. Calvanese V, et al. Among authors: fraga mf. Aging (Albany NY). 2011 Feb;3(2):162-7. doi: 10.18632/aging.100272. Aging (Albany NY). 2011. PMID: 21307403 Free PMC article.
Cancer genes hypermethylated in human embryonic stem cells.
Calvanese V, Horrillo A, Hmadcha A, Suarez-Alvarez B, Fernandez AF, Lara E, Casado S, Menendez P, Bueno C, Garcia-Castro J, Rubio R, Lapunzina P, Alaminos M, Borghese L, Terstegge S, Harrison NJ, Moore HD, Brüstle O, Lopez-Larrea C, Andrews PW, Soria B, Esteller M, Fraga MF. Calvanese V, et al. Among authors: fraga mf. PLoS One. 2008 Sep 29;3(9):e3294. doi: 10.1371/journal.pone.0003294. PLoS One. 2008. PMID: 18820729 Free PMC article.
Salermide, a Sirtuin inhibitor with a strong cancer-specific proapoptotic effect.
Lara E, Mai A, Calvanese V, Altucci L, Lopez-Nieva P, Martinez-Chantar ML, Varela-Rey M, Rotili D, Nebbioso A, Ropero S, Montoya G, Oyarzabal J, Velasco S, Serrano M, Witt M, Villar-Garea A, Imhof A, Mato JM, Esteller M, Fraga MF. Lara E, et al. Among authors: fraga mf. Oncogene. 2009 Feb 12;28(6):781-91. doi: 10.1038/onc.2008.436. Epub 2008 Dec 8. Oncogene. 2009. PMID: 19060927
New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling.
Martín-Subero JI, Kreuz M, Bibikova M, Bentink S, Ammerpohl O, Wickham-Garcia E, Rosolowski M, Richter J, Lopez-Serra L, Ballestar E, Berger H, Agirre X, Bernd HW, Calvanese V, Cogliatti SB, Drexler HG, Fan JB, Fraga MF, Hansmann ML, Hummel M, Klapper W, Korn B, Küppers R, Macleod RA, Möller P, Ott G, Pott C, Prosper F, Rosenwald A, Schwaenen C, Schübeler D, Seifert M, Stürzenhofecker B, Weber M, Wessendorf S, Loeffler M, Trümper L, Stein H, Spang R, Esteller M, Barker D, Hasenclever D, Siebert R; Molecular Mechanisms in Malignant Lymphomas Network Project of the Deutsche Krebshilfe. Martín-Subero JI, et al. Among authors: fraga mf. Blood. 2009 Mar 12;113(11):2488-97. doi: 10.1182/blood-2008-04-152900. Epub 2008 Dec 15. Blood. 2009. PMID: 19075189 Free article.
Genetic and epigenetic regulation of aging.
Fraga MF. Fraga MF. Curr Opin Immunol. 2009 Aug;21(4):446-53. doi: 10.1016/j.coi.2009.04.003. Epub 2009 Jun 6. Curr Opin Immunol. 2009. PMID: 19500963 Review.
The role of epigenetics in aging and age-related diseases.
Calvanese V, Lara E, Kahn A, Fraga MF. Calvanese V, et al. Among authors: fraga mf. Ageing Res Rev. 2009 Oct;8(4):268-76. doi: 10.1016/j.arr.2009.03.004. Epub 2009 Apr 1. Ageing Res Rev. 2009. PMID: 19716530 Review.
Epigenetic repression of ROR2 has a Wnt-mediated, pro-tumourigenic role in colon cancer.
Lara E, Calvanese V, Huidobro C, Fernández AF, Moncada-Pazos A, Obaya AJ, Aguilera O, González-Sancho JM, Sánchez L, Astudillo A, Muñoz A, López-Otín C, Esteller M, Fraga MF. Lara E, et al. Among authors: fraga mf. Mol Cancer. 2010 Jun 30;9:170. doi: 10.1186/1476-4598-9-170. Mol Cancer. 2010. PMID: 20591152 Free PMC article.
Sirtuin 1 regulation of developmental genes during differentiation of stem cells.
Calvanese V, Lara E, Suárez-Alvarez B, Abu Dawud R, Vázquez-Chantada M, Martínez-Chantar ML, Embade N, López-Nieva P, Horrillo A, Hmadcha A, Soria B, Piazzolla D, Herranz D, Serrano M, Mato JM, Andrews PW, López-Larrea C, Esteller M, Fraga MF. Calvanese V, et al. Among authors: fraga mf. Proc Natl Acad Sci U S A. 2010 Aug 3;107(31):13736-41. doi: 10.1073/pnas.1001399107. Epub 2010 Jul 14. Proc Natl Acad Sci U S A. 2010. PMID: 20631301 Free PMC article.
A promoter DNA demethylation landscape of human hematopoietic differentiation.
Calvanese V, Fernández AF, Urdinguio RG, Suárez-Alvarez B, Mangas C, Pérez-García V, Bueno C, Montes R, Ramos-Mejía V, Martínez-Camblor P, Ferrero C, Assenov Y, Bock C, Menendez P, Carrera AC, Lopez-Larrea C, Fraga MF. Calvanese V, et al. Among authors: fraga mf. Nucleic Acids Res. 2012 Jan;40(1):116-31. doi: 10.1093/nar/gkr685. Epub 2011 Sep 12. Nucleic Acids Res. 2012. PMID: 21911366 Free PMC article.
312 results