Ramachandran A - Search Results

1

HepaRG cells: a human model to study mechanisms of acetaminophen hepatotoxicity.

McGill MR, Yan HM, Ramachandran A, Murray GJ, Rollins DE, Jaeschke H. McGill MR, et al. Among authors: ramachandran a. Hepatology. 2011 Mar;53(3):974-82. doi: 10.1002/hep.24132. Epub 2011 Feb 11. Hepatology. 2011. PMID: 21319200 Free PMC article.

2

The oxygen tension modulates acetaminophen-induced mitochondrial oxidant stress and cell injury in cultured hepatocytes.

Yan HM, Ramachandran A, Bajt ML, Lemasters JJ, Jaeschke H. Yan HM, et al. Among authors: ramachandran a. Toxicol Sci. 2010 Oct;117(2):515-23. doi: 10.1093/toxsci/kfq208. Epub 2010 Jul 8. Toxicol Sci. 2010. PMID: 20616211 Free PMC article.

3

Cyclophilin D deficiency protects against acetaminophen-induced oxidant stress and liver injury.

Ramachandran A, Lebofsky M, Baines CP, Lemasters JJ, Jaeschke H. Ramachandran A, et al. Free Radic Res. 2011 Feb;45(2):156-64. doi: 10.3109/10715762.2010.520319. Epub 2010 Oct 13. Free Radic Res. 2011. PMID: 20942566 Free PMC article.

4

Reactive nitrogen species in acetaminophen-induced mitochondrial damage and toxicity in mouse hepatocytes: a cautionary note on the impact of cell culture conditions.

Jaeschke H, Yan HM, Ramachandran A. Jaeschke H, et al. Among authors: ramachandran a. Chem Res Toxicol. 2010 Dec 20;23(12):1853-4; author reply 1855-8. doi: 10.1021/tx100310b. Chem Res Toxicol. 2010. PMID: 21082831 No abstract available.

5

Reactive oxygen species in the normal and acutely injured liver.

Jaeschke H, Ramachandran A. Jaeschke H, et al. Among authors: ramachandran a. J Hepatol. 2011 Jul;55(1):227-8. doi: 10.1016/j.jhep.2011.01.006. Epub 2011 Jan 14. J Hepatol. 2011. PMID: 21238521 Free PMC article. No abstract available.

6

The impact of partial manganese superoxide dismutase (SOD2)-deficiency on mitochondrial oxidant stress, DNA fragmentation and liver injury during acetaminophen hepatotoxicity.

Ramachandran A, Lebofsky M, Weinman SA, Jaeschke H. Ramachandran A, et al. Toxicol Appl Pharmacol. 2011 Mar 15;251(3):226-33. doi: 10.1016/j.taap.2011.01.004. Epub 2011 Jan 15. Toxicol Appl Pharmacol. 2011. PMID: 21241727 Free PMC article.

7

Current issues with acetaminophen hepatotoxicity--a clinically relevant model to test the efficacy of natural products.

Jaeschke H, McGill MR, Williams CD, Ramachandran A. Jaeschke H, et al. Among authors: ramachandran a. Life Sci. 2011 Apr 25;88(17-18):737-45. doi: 10.1016/j.lfs.2011.01.025. Epub 2011 Feb 4. Life Sci. 2011. PMID: 21296090 Free PMC article. Review.

8

Pathophysiological relevance of proteomics investigations of drug-induced hepatotoxicity in HepG2 cells.

Jaeschke H, McGill MR, Ramachandran A. Jaeschke H, et al. Among authors: ramachandran a. Toxicol Sci. 2011 Jun;121(2):428-30; author reply 431-3. doi: 10.1093/toxsci/kfr053. Epub 2011 Mar 7. Toxicol Sci. 2011. PMID: 21385733 Free PMC article. No abstract available.

9

Apoptosis-inducing factor modulates mitochondrial oxidant stress in acetaminophen hepatotoxicity.

Bajt ML, Ramachandran A, Yan HM, Lebofsky M, Farhood A, Lemasters JJ, Jaeschke H. Bajt ML, et al. Among authors: ramachandran a. Toxicol Sci. 2011 Aug;122(2):598-605. doi: 10.1093/toxsci/kfr116. Epub 2011 May 13. Toxicol Sci. 2011. PMID: 21572097 Free PMC article.

10

Acetaminophen hepatotoxicity and repair: the role of sterile inflammation and innate immunity.

Jaeschke H, Williams CD, Ramachandran A, Bajt ML. Jaeschke H, et al. Among authors: ramachandran a. Liver Int. 2012 Jan;32(1):8-20. doi: 10.1111/j.1478-3231.2011.02501.x. Epub 2011 Mar 14. Liver Int. 2012. PMID: 21745276 Free PMC article. Review.

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