Yan HM - Search Results

1

HepaRG cells: a human model to study mechanisms of acetaminophen hepatotoxicity.

McGill MR, Yan HM, Ramachandran A, Murray GJ, Rollins DE, Jaeschke H. McGill MR, et al. Among authors: yan hm. Hepatology. 2011 Mar;53(3):974-82. doi: 10.1002/hep.24132. Epub 2011 Feb 11. Hepatology. 2011. PMID: 21319200 Free PMC article.

2

Bile Acid-Induced Toxicity in HepaRG Cells Recapitulates the Response in Primary Human Hepatocytes.

Woolbright BL, McGill MR, Yan H, Jaeschke H. Woolbright BL, et al. Basic Clin Pharmacol Toxicol. 2016 Feb;118(2):160-7. doi: 10.1111/bcpt.12449. Epub 2015 Aug 13. Basic Clin Pharmacol Toxicol. 2016. PMID: 26176423 Free PMC article.

3

Mechanism of protection by metallothionein against acetaminophen hepatotoxicity.

Saito C, Yan HM, Artigues A, Villar MT, Farhood A, Jaeschke H. Saito C, et al. Among authors: yan hm. Toxicol Appl Pharmacol. 2010 Jan 15;242(2):182-90. doi: 10.1016/j.taap.2009.10.006. Epub 2009 Oct 14. Toxicol Appl Pharmacol. 2010. PMID: 19835899 Free PMC article.

4

The oxygen tension modulates acetaminophen-induced mitochondrial oxidant stress and cell injury in cultured hepatocytes.

Yan HM, Ramachandran A, Bajt ML, Lemasters JJ, Jaeschke H. Yan HM, et al. Toxicol Sci. 2010 Oct;117(2):515-23. doi: 10.1093/toxsci/kfq208. Epub 2010 Jul 8. Toxicol Sci. 2010. PMID: 20616211 Free PMC article.

5

Apoptosis-inducing factor modulates mitochondrial oxidant stress in acetaminophen hepatotoxicity.

Bajt ML, Ramachandran A, Yan HM, Lebofsky M, Farhood A, Lemasters JJ, Jaeschke H. Bajt ML, et al. Among authors: yan hm. Toxicol Sci. 2011 Aug;122(2):598-605. doi: 10.1093/toxsci/kfr116. Epub 2011 May 13. Toxicol Sci. 2011. PMID: 21572097 Free PMC article.

6

Lysosomal instability and cathepsin B release during acetaminophen hepatotoxicity.

Woolbright BL, Ramachandran A, McGill MR, Yan HM, Bajt ML, Sharpe MR, Lemasters JJ, Jaeschke H. Woolbright BL, et al. Among authors: yan hm. Basic Clin Pharmacol Toxicol. 2012 Dec;111(6):417-25. doi: 10.1111/j.1742-7843.2012.00931.x. Epub 2012 Sep 25. Basic Clin Pharmacol Toxicol. 2012. PMID: 22900545 Free PMC article.

7

Hepatitis C virus structural proteins can exacerbate or ameliorate acetaminophen-induced liver injury in mice.

Ramachandran A, Lebofsky M, Yan HM, Weinman SA, Jaeschke H. Ramachandran A, et al. Among authors: yan hm. Arch Toxicol. 2015 May;89(5):773-83. doi: 10.1007/s00204-015-1498-5. Epub 2015 Mar 6. Arch Toxicol. 2015. PMID: 25743375 Free PMC article.

8

Plasminogen activator inhibitor-1 limits liver injury and facilitates regeneration after acetaminophen overdose.

Bajt ML, Yan HM, Farhood A, Jaeschke H. Bajt ML, et al. Among authors: yan hm. Toxicol Sci. 2008 Aug;104(2):419-27. doi: 10.1093/toxsci/kfn091. Epub 2008 May 9. Toxicol Sci. 2008. PMID: 18469330 Free PMC article.

9

Reactive nitrogen species in acetaminophen-induced mitochondrial damage and toxicity in mouse hepatocytes: a cautionary note on the impact of cell culture conditions.

Jaeschke H, Yan HM, Ramachandran A. Jaeschke H, et al. Among authors: yan hm. Chem Res Toxicol. 2010 Dec 20;23(12):1853-4; author reply 1855-8. doi: 10.1021/tx100310b. Chem Res Toxicol. 2010. PMID: 21082831 No abstract available.

10

Osteopontin is an initial mediator of inflammation and liver injury during obstructive cholestasis after bile duct ligation in mice.

Yang M, Ramachandran A, Yan HM, Woolbright BL, Copple BL, Fickert P, Trauner M, Jaeschke H. Yang M, et al. Among authors: yan hm. Toxicol Lett. 2014 Jan 13;224(2):186-95. doi: 10.1016/j.toxlet.2013.10.030. Epub 2013 Nov 2. Toxicol Lett. 2014. PMID: 24188933 Free PMC article.

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