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Page 1
Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma.
Keunen O, Johansson M, Oudin A, Sanzey M, Rahim SA, Fack F, Thorsen F, Taxt T, Bartos M, Jirik R, Miletic H, Wang J, Stieber D, Stuhr L, Moen I, Rygh CB, Bjerkvig R, Niclou SP. Keunen O, et al. Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3749-54. doi: 10.1073/pnas.1014480108. Epub 2011 Feb 14. Proc Natl Acad Sci U S A. 2011. PMID: 21321221 Free PMC article.
EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis.
Talasila KM, Soentgerath A, Euskirchen P, Rosland GV, Wang J, Huszthy PC, Prestegarden L, Skaftnesmo KO, Sakariassen PØ, Eskilsson E, Stieber D, Keunen O, Brekka N, Moen I, Nigro JM, Vintermyr OK, Lund-Johansen M, Niclou S, Mørk SJ, Enger PO, Bjerkvig R, Miletic H. Talasila KM, et al. Among authors: keunen o. Acta Neuropathol. 2013 May;125(5):683-98. doi: 10.1007/s00401-013-1101-1. Epub 2013 Feb 22. Acta Neuropathol. 2013. PMID: 23429996 Free PMC article.
Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas.
Fack F, Espedal H, Keunen O, Golebiewska A, Obad N, Harter PN, Mittelbronn M, Bähr O, Weyerbrock A, Stuhr L, Miletic H, Sakariassen PØ, Stieber D, Rygh CB, Lund-Johansen M, Zheng L, Gottlieb E, Niclou SP, Bjerkvig R. Fack F, et al. Among authors: keunen o. Acta Neuropathol. 2015 Jan;129(1):115-31. doi: 10.1007/s00401-014-1352-5. Epub 2014 Oct 17. Acta Neuropathol. 2015. PMID: 25322816 Free PMC article.
Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma.
Tardito S, Oudin A, Ahmed SU, Fack F, Keunen O, Zheng L, Miletic H, Sakariassen PØ, Weinstock A, Wagner A, Lindsay SL, Hock AK, Barnett SC, Ruppin E, Mørkve SH, Lund-Johansen M, Chalmers AJ, Bjerkvig R, Niclou SP, Gottlieb E. Tardito S, et al. Among authors: keunen o. Nat Cell Biol. 2015 Dec;17(12):1556-68. doi: 10.1038/ncb3272. Epub 2015 Nov 23. Nat Cell Biol. 2015. PMID: 26595383 Free PMC article.
Molecular crosstalk between tumour and brain parenchyma instructs histopathological features in glioblastoma.
Bougnaud S, Golebiewska A, Oudin A, Keunen O, Harter PN, Mäder L, Azuaje F, Fritah S, Stieber D, Kaoma T, Vallar L, Brons NH, Daubon T, Miletic H, Sundstrøm T, Herold-Mende C, Mittelbronn M, Bjerkvig R, Niclou SP. Bougnaud S, et al. Among authors: keunen o. Oncotarget. 2016 May 31;7(22):31955-71. doi: 10.18632/oncotarget.7454. Oncotarget. 2016. PMID: 27049916 Free PMC article.
EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.
Eskilsson E, Rosland GV, Talasila KM, Knappskog S, Keunen O, Sottoriva A, Foerster S, Solecki G, Taxt T, Jirik R, Fritah S, Harter PN, Välk K, Al Hossain J, Joseph JV, Jahedi R, Saed HS, Piccirillo SG, Spiteri I, Leiss L, Euskirchen P, Graziani G, Daubon T, Lund-Johansen M, Enger PØ, Winkler F, Ritter CA, Niclou SP, Watts C, Bjerkvig R, Miletic H. Eskilsson E, et al. Among authors: keunen o. Neuro Oncol. 2016 Dec;18(12):1644-1655. doi: 10.1093/neuonc/now113. Epub 2016 Jun 10. Neuro Oncol. 2016. PMID: 27286795 Free PMC article.
29 results