Smith AG - Search Results

1

Early failure of N-methyl-D-aspartate receptors and deficient spine formation induced by reduction of regulatory heme in neurons.

Chernova T, Steinert JR, Richards P, Mistry R, Challiss RA, Jukes-Jones R, Cain K, Smith AG, Forsythe ID. Chernova T, et al. Among authors: smith ag. Mol Pharmacol. 2011 May;79(5):844-54. doi: 10.1124/mol.110.069831. Epub 2011 Feb 15. Mol Pharmacol. 2011. PMID: 21325018

2

Heme deficiency is associated with senescence and causes suppression of N-methyl-D-aspartate receptor subunits expression in primary cortical neurons.

Chernova T, Nicotera P, Smith AG. Chernova T, et al. Among authors: smith ag. Mol Pharmacol. 2006 Mar;69(3):697-705. doi: 10.1124/mol.105.016675. Epub 2005 Nov 23. Mol Pharmacol. 2006. PMID: 16306232

3

Neurite degeneration induced by heme deficiency mediated via inhibition of NMDA receptor-dependent extracellular signal-regulated kinase 1/2 activation.

Chernova T, Steinert JR, Guerin CJ, Nicotera P, Forsythe ID, Smith AG. Chernova T, et al. Among authors: smith ag. J Neurosci. 2007 Aug 8;27(32):8475-85. doi: 10.1523/JNEUROSCI.0792-07.2007. J Neurosci. 2007. PMID: 17687025 Free PMC article.

4

Mevastatin accelerates loss of synaptic proteins and neurite degeneration in aging cortical neurons in a heme-independent manner.

Kannan M, Steinert JR, Forsythe ID, Smith AG, Chernova T. Kannan M, et al. Among authors: smith ag. Neurobiol Aging. 2010 Sep;31(9):1543-53. doi: 10.1016/j.neurobiolaging.2008.09.004. Epub 2008 Oct 31. Neurobiol Aging. 2010. PMID: 18951667

5

The regulatory role of heme in neurons.

Smith AG, Raven EL, Chernova T. Smith AG, et al. Metallomics. 2011 Oct;3(10):955-62. doi: 10.1039/c1mt00085c. Epub 2011 Sep 16. Metallomics. 2011. PMID: 21922110 Review.

6

Complex response to physiological and drug-induced hepatic heme demand in monoallelic ALAS1 mice.

Vagany V, Robinson S, Chernova T, Smith AG. Vagany V, et al. Among authors: smith ag. Mol Genet Metab Rep. 2021 Nov 12;29:100818. doi: 10.1016/j.ymgmr.2021.100818. eCollection 2021 Dec. Mol Genet Metab Rep. 2021. PMID: 34900592 Free PMC article.

7

Essential role of the AH receptor in the dysfunction of heme metabolism induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Davies R, Clothier B, Robinson SW, Edwards RE, Greaves P, Luo J, Gant TW, Chernova T, Smith AG. Davies R, et al. Among authors: smith ag. Chem Res Toxicol. 2008 Feb;21(2):330-40. doi: 10.1021/tx700176r. Epub 2007 Dec 29. Chem Res Toxicol. 2008. PMID: 18163543

8

B2 SINE retrotransposon causes polymorphic expression of mouse 5-aminolevulinic acid synthase 1 gene.

Chernova T, Higginson FM, Davies R, Smith AG. Chernova T, et al. Among authors: smith ag. Biochem Biophys Res Commun. 2008 Dec 12;377(2):515-520. doi: 10.1016/j.bbrc.2008.10.020. Epub 2008 Oct 16. Biochem Biophys Res Commun. 2008. PMID: 18929534 Free article.

9

Hepatic gene expression in protoporphyic Fech mice is associated with cholestatic injury but not a marked depletion of the heme regulatory pool.

Davies R, Schuurman A, Barker CR, Clothier B, Chernova T, Higginson FM, Judah DJ, Dinsdale D, Edwards RE, Greaves P, Gant TW, Smith AG. Davies R, et al. Among authors: smith ag. Am J Pathol. 2005 Apr;166(4):1041-53. doi: 10.1016/S0002-9440(10)62325-5. Am J Pathol. 2005. PMID: 15793285 Free PMC article.

10

Interaction between iron metabolism and 2,3,7,8-tetrachlorodibenzo-p-dioxin in mice with variants of the Ahr gene: a hepatic oxidative mechanism.

Smith AG, Clothier B, Robinson S, Scullion MJ, Carthew P, Edwards R, Luo J, Lim CK, Toledano M. Smith AG, et al. Mol Pharmacol. 1998 Jan;53(1):52-61. doi: 10.1124/mol.53.1.52. Mol Pharmacol. 1998. PMID: 9443932

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