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In vivo demonstration that alpha-synuclein oligomers are toxic.
Winner B, Jappelli R, Maji SK, Desplats PA, Boyer L, Aigner S, Hetzer C, Loher T, Vilar M, Campioni S, Tzitzilonis C, Soragni A, Jessberger S, Mira H, Consiglio A, Pham E, Masliah E, Gage FH, Riek R. Winner B, et al. Among authors: maji sk. Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):4194-9. doi: 10.1073/pnas.1100976108. Epub 2011 Feb 15. Proc Natl Acad Sci U S A. 2011. PMID: 21325059 Free PMC article.
Distinct structural and functional roles of conserved residues in the first extracellular domain of receptors for corticotropin-releasing factor and related G-protein-coupled receptors.
Perrin MH, Grace CR, Digruccio MR, Fischer WH, Maji SK, Cantle JP, Smith S, Manning G, Vale WW, Riek R. Perrin MH, et al. Among authors: maji sk. J Biol Chem. 2007 Dec 28;282(52):37529-36. doi: 10.1074/jbc.M703748200. Epub 2007 Oct 16. J Biol Chem. 2007. PMID: 17940290 Free article.
The fold of alpha-synuclein fibrils.
Vilar M, Chou HT, Lührs T, Maji SK, Riek-Loher D, Verel R, Manning G, Stahlberg H, Riek R. Vilar M, et al. Among authors: maji sk. Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8637-42. doi: 10.1073/pnas.0712179105. Epub 2008 Jun 12. Proc Natl Acad Sci U S A. 2008. PMID: 18550842 Free PMC article.
Bacterial inclusion bodies contain amyloid-like structure.
Wang L, Maji SK, Sawaya MR, Eisenberg D, Riek R. Wang L, et al. Among authors: maji sk. PLoS Biol. 2008 Aug 5;6(8):e195. doi: 10.1371/journal.pbio.0060195. PLoS Biol. 2008. PMID: 18684013 Free PMC article.
Structure-activity relationship of amyloid fibrils.
Maji SK, Wang L, Greenwald J, Riek R. Maji SK, et al. FEBS Lett. 2009 Aug 20;583(16):2610-7. doi: 10.1016/j.febslet.2009.07.003. Epub 2009 Jul 14. FEBS Lett. 2009. PMID: 19596006 Free article. Review.
α-Synuclein aggregation nucleates through liquid-liquid phase separation.
Ray S, Singh N, Kumar R, Patel K, Pandey S, Datta D, Mahato J, Panigrahi R, Navalkar A, Mehra S, Gadhe L, Chatterjee D, Sawner AS, Maiti S, Bhatia S, Gerez JA, Chowdhury A, Kumar A, Padinhateeri R, Riek R, Krishnamoorthy G, Maji SK. Ray S, et al. Among authors: maji sk. Nat Chem. 2020 Aug;12(8):705-716. doi: 10.1038/s41557-020-0465-9. Epub 2020 Jun 8. Nat Chem. 2020. PMID: 32514159
The three-dimensional structure of human β-endorphin amyloid fibrils.
Seuring C, Verasdonck J, Gath J, Ghosh D, Nespovitaya N, Wälti MA, Maji SK, Cadalbert R, Güntert P, Meier BH, Riek R. Seuring C, et al. Among authors: maji sk. Nat Struct Mol Biol. 2020 Dec;27(12):1178-1184. doi: 10.1038/s41594-020-00515-z. Epub 2020 Oct 12. Nat Struct Mol Biol. 2020. PMID: 33046908
136 results