Ley SV - Search Results

1

Allosteric modulation of hormone release from thyroxine and corticosteroid-binding globulins.

Qi X, Loiseau F, Chan WL, Yan Y, Wei Z, Milroy LG, Myers RM, Ley SV, Read RJ, Carrell RW, Zhou A. Qi X, et al. Among authors: ley sv. J Biol Chem. 2011 May 6;286(18):16163-73. doi: 10.1074/jbc.M110.171082. Epub 2011 Feb 16. J Biol Chem. 2011. PMID: 21325280 Free PMC article.

2

Chemical variation of natural product-like scaffolds: design and synthesis of spiroketal derivatives.

Zinzalla G, Milroy LG, Ley SV. Zinzalla G, et al. Among authors: ley sv. Org Biomol Chem. 2006 May 21;4(10):1977-2002. doi: 10.1039/b603015g. Epub 2006 Apr 21. Org Biomol Chem. 2006. PMID: 16688343

3

Total syntheses of subereamollines A and B.

Shearman JW, Myers RM, Brenton JD, Ley SV. Shearman JW, et al. Among authors: ley sv. Org Biomol Chem. 2011 Jan 7;9(1):62-5. doi: 10.1039/c0ob00636j. Epub 2010 Oct 15. Org Biomol Chem. 2011. PMID: 20953439

4

Flow chemistry meets advanced functional materials.

Myers RM, Fitzpatrick DE, Turner RM, Ley SV. Myers RM, et al. Among authors: ley sv. Chemistry. 2014 Sep 22;20(39):12348-66. doi: 10.1002/chem.201402801. Epub 2014 Aug 25. Chemistry. 2014. PMID: 25156609

5

Design, synthesis, and biological evaluation of an allosteric inhibitor of HSET that targets cancer cells with supernumerary centrosomes.

Watts CA, Richards FM, Bender A, Bond PJ, Korb O, Kern O, Riddick M, Owen P, Myers RM, Raff J, Gergely F, Jodrell DI, Ley SV. Watts CA, et al. Among authors: ley sv. Chem Biol. 2013 Nov 21;20(11):1399-410. doi: 10.1016/j.chembiol.2013.09.012. Epub 2013 Oct 24. Chem Biol. 2013. PMID: 24210220 Free PMC article.

6

Natural-product-like spiroketals and fused bicyclic acetals as potential therapeutic agents for B-cell chronic lymphocytic leukaemia.

Milroy LG, Zinzalla G, Loiseau F, Qian Z, Prencipe G, Pepper C, Fegan C, Ley SV. Milroy LG, et al. Among authors: ley sv. ChemMedChem. 2008 Dec;3(12):1922-35. doi: 10.1002/cmdc.200800265. ChemMedChem. 2008. PMID: 19025736

7

Cancer, chemistry, and the cell: molecules that interact with the neurotensin receptors.

Myers RM, Shearman JW, Kitching MO, Ramos-Montoya A, Neal DE, Ley SV. Myers RM, et al. Among authors: ley sv. ACS Chem Biol. 2009 Jul 17;4(7):503-25. doi: 10.1021/cb900038e. ACS Chem Biol. 2009. PMID: 19462983 Review.

8

Increased endothelial cell selectivity of triazole-bridged dihalogenated A-ring analogues of combretastatin A-1.

Beale TM, Bond PJ, Brenton JD, Charnock-Jones DS, Ley SV, Myers RM. Beale TM, et al. Among authors: ley sv. Bioorg Med Chem. 2012 Mar 1;20(5):1749-59. doi: 10.1016/j.bmc.2012.01.010. Epub 2012 Jan 18. Bioorg Med Chem. 2012. PMID: 22304851

9

Organic synthesis: march of the machines.

Ley SV, Fitzpatrick DE, Ingham RJ, Myers RM. Ley SV, et al. Angew Chem Int Ed Engl. 2015 Mar 9;54(11):3449-64. doi: 10.1002/anie.201410744. Epub 2015 Jan 13. Angew Chem Int Ed Engl. 2015. PMID: 25586940

10

Machine-Assisted Organic Synthesis.

Ley SV, Fitzpatrick DE, Myers RM, Battilocchio C, Ingham RJ. Ley SV, et al. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10122-36. doi: 10.1002/anie.201501618. Epub 2015 Jul 16. Angew Chem Int Ed Engl. 2015. PMID: 26193360 Free PMC article. Review.

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